Acute platelet depletion rapidly recruits quiescent HSCs into proliferationIn line with previous studies9, administration of a single dose of anti-GPIbα antibody to Vwf-GFP mice,...
Dear Editor,Hematopoietic stem cells (HSCs) residing in adult mouse bone marrow (BM) are highly heterogenous,1 ranging from HSCs executing their full multilineage potential to...
F16BP microparticles are in phagocytosable rangeTo demonstrate the strength of such a strategy PFK15 (blocks−6-Phosphofructo-2-Kinase Fructose-2,6-Biphosphatase 3-PFKFB3) was chosen to block glycolysis, as it...
Yeast lacking the C-5 sterol desaturase Erg3 exhibit striking enhanced tolerance to escinWe hypothesised that if escin toxicity is mediated by direct interaction with...
Heterogeneous fibroblasts contribute to lizard tail regrowthTo investigate the complexity and heterogeneity of each regeneration state during tail regrowth, we performed single-cell RNA sequencing...
Dear Editor,Sebaceous glands (SG) contribute to 90% of the skin surface lipid production and play critical roles in regulating proper skin functions including epidermal...
CITE-seq provides a comprehensive representation of EHTTo define factors in the endothelium that prime cells towards a hemogenic phenotype, we performed CITE-seq on CD31+ FACS-isolated...
Mutation of NPM1 results in cytoplasmic sequestration of NPM1C+ protein that maintains a unique expression pattern of HOXA/B genes and MEIS1 oncogene by directly...
Acute muscle injury induces Hedgehog activation, via its ligand DHH, to repress IMAT formationThe identity of the endogenous Hh ligand, and its producing cell...
