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Tag: 2C

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner – Nature Communications

Acute platelet depletion rapidly recruits quiescent HSCs into proliferationIn line with previous studies9, administration of a single dose of anti-GPIbα antibody to Vwf-GFP mice,...

Deglycosylation of eukaryotic-expressed flagellin restores adjuvanticity – npj Vaccines

EthicsAll animal experimental procedures were approved by the Chonnam National University Institutional Animal Care and Use Committee under the protocol CNU IACUC-H-2021-51. Animal research...

Rapid, tunable, and multiplexed detection of RNA using convective array PCR – Communications Biology

Integrating reverse transcription in caPCRWe first introduced an RT step to the standard caPCR assay. caPCR is performed using a set of 4 heaters...

Abnormal developmental trajectory and vulnerability to cardiac arrhythmias in tetralogy of Fallot with DiGeorge syndrome – Communications Biology

Generation and characterisation of patient-specific hiPSCs and hiPSC-CMshiPSC lines were established from two TOF-DG patients, two TOF-ND patients, and two healthy controls with pluripotency...

Ascl1 and Ngn2 convert mouse embryonic stem cells to neurons via functionally distinct paths – Nature Communications

Ascl1 and Ngn2 convert ESC to iN but generate different side lineagesEctopic expression of Ascl1 or Ngn2 in mouse embryonic stem cells (ESCs) is...

Yeast lacking the sterol C-5 desaturase Erg3 are tolerant to the anti-inflammatory triterpenoid saponin escin – Scientific Reports

Yeast lacking the C-5 sterol desaturase Erg3 exhibit striking enhanced tolerance to escinWe hypothesised that if escin toxicity is mediated by direct interaction with...

ATF3 induction prevents precocious activation of skeletal muscle stem cell by regulating H2B expression – Nature Communications

ATF3 is rapidly and transiently induced during SC early activationTo explore the transcriptional regulatory events governing the SC quiescence-to-activation transition, we re-analyzed our previously...

Iridescent biofilms of Cellulophaga lytica are tunable platforms for scalable, ordered materials – Scientific Reports

Biofilm propertiesCellulophaga lytica 7489 biofilms grown for 24 h on BB2/H2O media containing various agar concentrations were compared (Fig. 1A, B). Color patterns differed after 5 days...

SNIP1 and PRC2 coordinate cell fates of neural progenitors during brain development – Nature Communications

SNIP1 is required for the survival of NPCs in the murine embryonic brainWe first examined the expression of Snip1 in the murine embryonic brain...

Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles – Nature Communications

A simple assay for screening EV-sorting proteinsIn search of efficient EV-sorting proteins, a list of candidates was compiled based on literature review and proteomics...

Intel’s next-next gen Lunar Lake architectural details surface

Intel's roadmap is a little confusing, at least for those of us looking in from the outside. There are so many lakes, you'd be...

July 30: Prepare for Blackouts! Massive Heatwave, Another Bank Collapses, Cities Bankrupt Next? (Recap ep238) – Investing & Day Trading Education: Day Trading Academy

In today’s recap, Marcello tells us to be prepared in case of possible blackouts due to the heat wave affecting the world and especially...

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