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Tag: stem cells

Certainty, wine and haematology – Bone Marrow Transplantation

Pliny the ElderNatural Philosopher AD 23/79. In these matters the only certainty is that nothing is certain. Pliny the Elder was a man of...

Weekly reads: stem cells for MS, Kimera Labs IND, FDA lawsuit – The Niche

There has been a steady stream of encouraging data on stem cells for MS. Particularly for certain kinds of MS. A new study adds to...

IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration – Nature Communications

MiceYoung (2–4 months old) and old (18–26 months old) male and female wild-type C57BL6/J, Lgr5-ki-eGFP-creER, and Olfm4-ki-eGFP-creER mice were group housed and maintained in...

CIRM invests nearly $44 million to advance regenerative medicine research and manufacturing in California

September 29, 2023 South San Francisco, CA –  The California Institute for Regenerative Medicine (CIRM), the world’s largest institution dedicated to regenerative medicine,...

An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration – npj Regenerative Medicine

Tzioupis, C. & Giannoudis, P. V. Prevalence of long-bone non-unions. Injury 38, S3–S9 (2007).Article  PubMed  Google Scholar  Calori, G. M., Mazza, E., Colombo,...

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner – Nature Communications

Acute platelet depletion rapidly recruits quiescent HSCs into proliferationIn line with previous studies9, administration of a single dose of anti-GPIbα antibody to Vwf-GFP mice,...

Eight anti-aging startups on a mission to extend lives

The longevity biotech industry revolves around the goal of increasing the period of life that a person spends in good health. There has been...

BrainStorm Cell Therapeutics Hail Mary with FDA on Nurown for ALS – The Niche

BrainStorm Cell Therapeutics is developing Nurown, an investigational therapy intended for treating ALS. I recently posted about BrainStorm and its prospects for providing real hope...

Human embryo models offer glimpse into early development

RESEARCH HIGHLIGHT 25 September 2023 Grown from stem cells, the models recapitulate the hallmarks of post-implantation human embryos up to...

Weekly reads: artificial wombs, mice with rat brains, Neuralink – The Niche

It feels like we are marching towards a future in which key aspects of human reproduction, including the use of artificial wombs, could be...

Novo Nordisk parent backs cell therapy manufacturing facility

Dive Brief: The Novo Nordisk Foundation, the controlling owner of the Danish drugmaker, will spend up to 950 million kroner, or roughly $136 million, to...

Burst Biologics unapproved biologic used by Weill Cornell: was there a cover-up? – The Niche

The New York Times just broke a story on Burst Biologics and Weill Cornell that fits with long-standing troubling questions about regenerative biologics producers....

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