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Tag: gene expression

Intracerebral fate of organic and inorganic nanoparticles is dependent on microglial extracellular vesicle function – Nature Nanotechnology

Zheng, M., Tao, W., Zou, Y., Farokhzad, O. C. & Shi, B. Nanotechnology-based strategies for siRNA brain delivery for disease therapy. Trends Biotechnol. 36,...

Strategies for non-viral vectors targeting organs beyond the liver – Nature Nanotechnology

Zhang, Y.-N., Poon, W., Tavares, A. J., McGilvray, I. D. & Chan, W. C. W. Nanoparticle–liver interactions: cellular uptake and hepatobiliary elimination. J. Control....

The Biggest Discoveries in Biology in 2023 | Quanta Magazine

IntroductionRevolutions in the biological sciences can take many forms. Sometimes they erupt from the use of a novel tool or the invention of a...

From Longevity To Aging In Place, These Are The Top Areas For Senior-Focused Startups

Anyone who follows demographic trends is probably aware that the population of older adults in the U.S. and other advanced economies is growing at...

New Cell Atlases Reveal Untold Variety in the Brain and Beyond | Quanta Magazine

IntroductionIn the 16th century, the Belgian cartographer Abraham Ortelius created the world’s first modern atlas — a collection of maps that he called “The...

Mice Just Passed the Mirror Test. Here’s What That Says About Our Sense of Self

Here’s a fun test: Dab some blush onto the forehead of a six-month-old baby and plop them in front of a mirror. They might...

Patent Office Issued 225 Patents to Indiana Entities in September 2023

The U.S. Patent Office issued the following 225 patents to persons and businesses in Indiana in September 2023: Patent Number                             Patent Title US 11766015 B1 Maize hybrid X13R074 US...

FDA staff focus on ‘off-target’ risk in review of Vertex, CRISPR sickle cell therapy

Food and Drug Administration scientists are scrutinizing whether an experimental gene editing therapy for sickle cell disease makes unwanted changes to DNA as part...

Proton therapy on an upward trajectory while FLASH treatment schemes get ready to shine – Physics World

Innovation in proton therapy was front-and-centre at the ASTRO Annual Meeting, along with advances in other cutting-edge modalities – among them...

Leukemia & Hemp Derived CBD

CANCER x STATS Cancer has become a major public health concern in the United States and around the globe. It is estimated that one in...

Multivalent insulin receptor activation using insulin–DNA origami nanostructures – Nature Nanotechnology

Cell cultureBrown adipocytes were differentiated from an immortalized brown preadipocyte mouse cell line kindly provided by B. Spiegelman (Harvard University) as previously described19. Preadipocytes...

IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration – Nature Communications

MiceYoung (2–4 months old) and old (18–26 months old) male and female wild-type C57BL6/J, Lgr5-ki-eGFP-creER, and Olfm4-ki-eGFP-creER mice were group housed and maintained in...

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