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Tag: gene expression

Human Artificial Chromosomes Could Ferry Tons More DNA Cargo Into Cells

The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA...

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Tiny Tweaks to Neurons Can Rewire Animal Motion | Quanta Magazine

IntroductionIn March 2019, on a train headed southwest from Munich, the neuroscientist Maximilian Bothe adjusted his careful grip on the cooler in his lap....

Physics sing-along is coming to Minneapolis, tiny fish creates very loud sounds – Physics World

Those attending the American Physical Society (APS) March meeting at the Minneapolis Convention Center next week will no doubt be looking forward to the...

Gene Silencing Slashes Cholesterol in Mice—No Gene Edits Required

With just one shot, scientists have slashed cholesterol levels in mice. The treatment lasted for at least half their lives.The shot may sound like...

A ‘Lobby’ Where a Molecule Mob Tells Genes What to Do | Quanta Magazine

IntroductionThe discovery during the Human Genome Project in the early 2000s that we humans have only about 20,000 protein-coding genes — about as many...

Researchers develop groundbreaking technique to detect chemoresistance using ultrasound

Researchers at Purdue University have developed a technique to better predict chemotherapy resistance in canines and humans. Chemotherapy can save lives, but often a cancer...

Evidence and therapeutic implications of biomechanically regulated immunosurveillance in cancer and other diseases – Nature Nanotechnology

Klotter, V. et al. Assessment of pathologic increase in liver stiffness enables earlier diagnosis of CFLD: results from a prospective longitudinal cohort study. PLoS...

Intracerebral fate of organic and inorganic nanoparticles is dependent on microglial extracellular vesicle function – Nature Nanotechnology

Zheng, M., Tao, W., Zou, Y., Farokhzad, O. C. & Shi, B. Nanotechnology-based strategies for siRNA brain delivery for disease therapy. Trends Biotechnol. 36,...

Strategies for non-viral vectors targeting organs beyond the liver – Nature Nanotechnology

Zhang, Y.-N., Poon, W., Tavares, A. J., McGilvray, I. D. & Chan, W. C. W. Nanoparticle–liver interactions: cellular uptake and hepatobiliary elimination. J. Control....

The Biggest Discoveries in Biology in 2023 | Quanta Magazine

IntroductionRevolutions in the biological sciences can take many forms. Sometimes they erupt from the use of a novel tool or the invention of a...

From Longevity To Aging In Place, These Are The Top Areas For Senior-Focused Startups

Anyone who follows demographic trends is probably aware that the population of older adults in the U.S. and other advanced economies is growing at...

New Cell Atlases Reveal Untold Variety in the Brain and Beyond | Quanta Magazine

IntroductionIn the 16th century, the Belgian cartographer Abraham Ortelius created the world’s first modern atlas — a collection of maps that he called “The...

Mice Just Passed the Mirror Test. Here’s What That Says About Our Sense of Self

Here’s a fun test: Dab some blush onto the forehead of a six-month-old baby and plop them in front of a mirror. They might...

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