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Tag: deliv

3D-bioprinted cancer-on-a-chip: level-up organotypic in vitro models

Whiteside T.L. The tumor microenvironment and its role in promoting tumor growth.Oncogene. 2008; 27: 5904-5912Duan Q. et al.Turning cold into hot: firing up...

Discovery and delivery strategies for engineered live biotherapeutic products

Food and Drug Administration Early Clinical Trials with Live Biotherapeutic Products: Chemistry, Manufacturing, and Control Information. FDA, 2016O’Toole P.W. et al.Next-generation probiotics: the...

Regenerating dynamic organs using biomimetic patches

Lakshmanan R. et al.Living cardiac patch: the elixir for cardiac regeneration.Expert. Opin. Biol. Ther. 2012; 12: 1623-1640Bolonduro O.A. et al.From biomimicry to bioelectronics:...

Role of bacterial motility in differential resistance mechanisms of silver nanoparticles and silver ions

1. Mijnendonckx, K., Leys, N., Mahillon, J., Silver, S. & Van Houdt, R. Antimicrobial silver: uses, toxicity and potential for resistance. BioMetals 26, 609–621...

X-ray-activated persistent luminescence nanomaterials for NIR-II imaging

1.Hong, G., Antaris, A. L. & Dai, H. Near-infrared fluorophores for biomedical imaging. Nat. Biomed. Eng. 1, 0010 (2017).CAS  Article  Google Scholar ...

The current landscape of nucleic acid therapeutics

1.Friedmann, T. & Roblin, R. Gene therapy for human genetic disease? Science 175, 949–955 (1972).CAS  Article  Google Scholar  2.Anderson, E. J. et...

Bioorthogonal catalytic patch

1.Li, J. & Chen, P. R. Development and application of bond cleavage reactions in bioorthogonal chemistry. Nat. Chem. Biol. 12, 129–137 (2016).CAS  ...

Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer

1.Davidson, S. M. et al. Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors. Nat. Med. 23, 235–241 (2017).CAS  Article  Google...

Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours

1.Delgado-Lopez, P. D. & Corrales-Garcia, E. M. Survival in glioblastoma: a review on the impact of treatment modalities. Clin. Transl. Oncol. 18, 1062–1071...

Ultra-high-frequency radio-frequency acoustic molecular imaging with saline nanodroplets in living subjects

1.Gambhir, S. S., Ge, T. J., Vermesh, O. & Spitler, R. Toward achieving precision health. Sci. Transl. Med. 10, eaao3612 (2018).Article  Google...

Nanotechnology approaches for global infectious diseases

1.Roth, G. A. et al. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a...

Key principles and methods for studying the endocytosis of biological and nanoparticle therapeutics

1.Karasneh, G. A. & Shukla, D. Herpes simplex virus infects most cell types in vitro: clues to its success. Virol. J. 8, 481...

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