The tumor microenvironment and its role in promoting tumor growth.
Oncogene. 2008; 27: 5904-5912
Turning cold into hot: firing up the tumor microenvironment.
Trends Cancer. 2020; 6: 605-618
Physical traits of cancer.
Science. 2020; 370: 6516
Biophysics of tumor microenvironment and cancer metastasis – a mini review.
Comput. Struct. Biotechnol. J. 2018; 16: 279-287
Cross-talk between the tumor microenvironment, extracellular matrix, and cell metabolism in cancer.
Front. Oncol. 2020; 10: 1-7
The biology and function of fibroblasts in cancer.
Nat. Rev. Cancer. 2016; 16: 582-598
Stratified 3D microtumors as organotypic testing platforms for screening pancreatic cancer therapies.
Small Methods. 2021; 52001207
Three-dimensional in vitro cancer models: a short review.
Biofabrication. 2014; 6022001
Tumor organoids: from inception to future in cancer research.
Cancer Lett. 2019; 454: 120-133
3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs.
Biotechnol. Bioeng. 2019; 116: 206-226
Design of spherically structured 3D in vitro tumor models -advances and prospects.
Acta Biomater. 2018; 75: 11-34
Organotypic cancer tissue models for drug screening: 3D constructs, bioprinting and microfluidic chips.
Drug Discov. Today. 2020; 25: 879-890
Bioinstructive microparticles for self-assembly of mesenchymal stem cell-3D tumor spheroids.
Biomaterials. 2018; 185: 155-173
Emerging organoid models: leaping forward in cancer research.
J. Hematol. Oncol. 2019; 12: 1-10
Translating complexity and heterogeneity of pancreatic tumor: 3D in vitro to in vivo models.
Adv. Drug Deliv. Rev. 2021; 174: 265-293
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture.
Nat. Med. 2014; 20: 769-777
Engineered materials for organoid systems.
Nat. Rev. Mater. 2019; 4: 606-622
Cancer modeling meets human organoid technology.
Science. 2019; 364: 952-955
Organoid-on-a-chip and body-on-a- chip systems for drug screening and disease modeling.
Drug Discov. Today. 2016; 21: 1399-1411
Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models.
BMC Cancer. 2018; 18: 1-13
Bioinspired biomaterials to develop cell-rich spherical microtissues for 3D in vitro tumor modeling.
in: Kundu S.C. Reis R.L. Biomaterials for 3D Tumor Modeling. Elsevier, 2020: 43-65
ECM and ECM-like materials — biomaterials for applications in regenerative medicine and cancer therapy.
Adv. Drug Deliv. Rev. 2016; 97: 260-269
Heralding a new paradigm in 3D tumor modeling.
Biomaterials. 2016; 108: 197-213
Engineering 3D hydrogels for personalized in vitro human tissue models.
Adv. Healthc. Mater. 2018; 71701165
A practical guide to hydrogels for cell culture.
Nat. Methods. 2016; 13: 405-414
Biomimetic and enzyme-responsive dynamic hydrogels for studying cell-matrix interactions in pancreatic ductal adenocarcinoma.
Biomaterials. 2018; 160: 24-36
Modelling cancer in microfluidic human organs-on-chips.
Nat. Rev. Cancer. 2019; 19: 65-81
Modeling tumor phenotypes in vitro with three-dimensional bioprinting.
Cell Rep. 2019; 26: 608-623
Dynamic bioinks to advance bioprinting.
Adv. Healthc. Mater. 2020; 91901798
3D-bioprinted mini-brain: a glioblastoma model to study cellular interactions and therapeutics.
Adv. Mater. 2019; 311806590
Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting.
Proc. Natl. Acad. Sci. U. S. A. 2016; 113: 2206-2211
Tumor cell cycle arrest induced by shear stress: roles of integrins and Smad.
Proc. Natl. Acad. Sci. U. S. A. 2008; 105: 3927-3932
Cancer cells grown in 3D under fluid flow exhibit an aggressive phenotype and reduced responsiveness to the anti-cancer treatment doxorubicin.
Sci. Rep. 2020; 10: 1-10
Microfluidic bioprinting for organ-on-a-chip models.
Drug Discov. Today. 2019; 24: 1248-1258
Applications of tumor chip technology.
Lab Chip. 2018; 18: 2893-2912
Mechanical stimulation: a crucial element of organ-on-chip models.
Front. Bioeng. Biotechnol. 2020; 8: 1426
Methods of delivering mechanical stimuli to organ-on-a-chip.
Micromachines. 2019; 10: 700
Small force, big impact: next generation organ-on-a-chip systems incorporating biomechanical cues.
Front. Physiol. 2018; 9: 1417
Reconstituting organ-level lung functions on a chip.
Science. 2010; 328: 1662-1668
A human disease model of drug toxicity–induced pulmonary edema in a lung-on-a-chip microdevice.
Sci. Transl. Med. 2012; 4159ra147
Bioprinting of 3D tissues/organs combined with microfluidics.
RSC Adv. 2018; 8: 21712-21727
Engineering in vitro human tissue models through bio-design and manufacturing.
Bio-Design Manuf. 2020; 3: 155-159
3D Bioprinting and its application to organ-on-a-chip.
Microelectron. Eng. 2018; 200: 1-11
Novel strategies in artificial organ development: what is the future of medicine?.
Micromachines. 2020; 11: 1-29
Multivascular networks and functional intravascular topologies within biocompatible hydrogels.
Science. 2019; 364: 458-464
A tumor-on-a-chip system with bioprinted blood and lymphatic vessel pair.
Adv. Funct. Mater. 2019; 291807173
3D bioprinting for modelling vasculature.
Microphysiol. Syst. 2018; 2: 9
Three-dimensional bioprinting of thick vascularized tissues.
Proc. Natl. Acad. Sci. U. S. A. 2016; 113: 3179-3184
Improving bioprinted volumetric tumor microenvironments in vitro.
Trends Cancer. 2020; 6: 745-756
Advanced bottom-up engineering of living architectures.
Adv. Mater. 2019; 321903975
The prognostic value of tumour-stroma ratio in triple-negative breast cancer.
Eur. J. Surg. Oncol. 2012; 38: 307-313
Heterotypic 3D pancreatic cancer model with tunable proportion of fibrotic elements.
Biomaterials. 2020; 251120077
Artificial intelligence quantified tumour-stroma ratio is an independent predictor for overall survival in resectable colorectal cancer.
EBioMedicine. 2020; 61103054
Tumour stroma ratio assessment using digital image analysis predicts survival in triple negative and luminal breast cancer.
Cancers (Basel). 2020; 12: 3749
The tumor profiler study: integrated, multi-omic, functional tumor profiling for clinical decision support.
Cancer Cell. 2021; 39: 288-293
A quantitative analysis of the interplay of environment, neighborhood, and cell state in 3D spheroids.
Mol. Syst. Biol. 2020; 16e9798
Bioink properties before, during and after 3D bioprinting.
Biofabrication. 2016; 8032002
Recent trends in bioinks for 3D printing.
22. 2018: 1-15
Bioinks for 3D bioprinting: an overview.
Biomater. Sci. 2018; 6: 915-946
Decellularized extracellular matrix for bioengineering physiomimetic 3D in vitro tumor models.
Trends Biotechnol. 2020; 38: 1-18
An injectable alginate/extra cellular matrix (ECM) hydrogel towards acellular treatment of heart failure.
Drug Deliv. Transl. Res. 2019; 9: 1-13
3D bioprinting of low-concentration cell-laden gelatin methacrylate (GelMA) bioinks with a two-step cross-linking strategy.
ACS Appl. Mater. Interfaces. 2018; 10: 6849-6857
Designer hydrogels: shedding light on the physical chemistry of the pancreatic cancer microenvironment.
Cancer Lett. 2018; 436: 22-27
A photo-crosslinkable kidney ECM-derived bioink accelerates renal tissue formation.
Adv. Healthc. Mater. 2019; 8: 1-10
Voxelated soft matter via multimaterial multinozzle 3D printing.
Nature. 2019; 575: 330-335
Development of a disposable single-nozzle printhead for 3D bioprinting of continuous multi-material constructs.
Micromachines. 2020; 11: 459
Zhang, Y.S. and Khademhosseini, A. The Brigham and Women’s Hospital. Systems and methods for in vivo multi-material bioprinting, WO201784839A1
Bioprinters for organs-on-chips.
Biofabrication. 2019; 11: 42002
A combined 3D printing/CNC micro-milling method to fabricate a large-scale microfluidic device with the small size 3D architectures: an application for tumor spheroid production.
Sci. Rep. 2020; 10: 1-14
Towards single-step biofabrication of organs on a chip via 3D printing.
Trends Biotechnol. 2016; 34: 685-688
3D bioprinting for reconstituting the cancer microenvironment.
NPJ Precis. Oncol. 2020; 4: 18
Combining additive manufacturing with microfluidics: an emerging method for developing novel organs-on-chips.
Curr. Opin. Chem. Eng. 2020; 28: 1-9
One-step fabrication of an organ-on-a-chip with spatial heterogeneity using a 3D bioprinting technology.
Lab Chip. 2016; 16: 2618-2625
3D cell-printed hypoxic cancer-on-a-chip for recapitulating pathologic progression of solid cancer.
J. Vis. Exp. 2021; ()
Recent advances in nonbiofouling PDMS surface modification strategies applicable to microfluidic technology.
Technology. 2017; 5: 1-12
Simulating drug concentrations in PDMS microfluidic organ chips.
Lab Chip. 2021; ()
Fabrication of whole-thermoplastic normally closed microvalve, micro check valve, and micropump.
Sensors Actuators B Chem. 2018; 262: 625-636
Rapid prototyping of whole-thermoplastic microfluidics with built-in microvalves using laser ablation and thermal fusion bonding.
Sensors Actuators B Chem. 2018; 255: 100-109
Beyond polydimethylsiloxane: alternative materials for fabrication of organ-on-a-chip devices and microphysiological systems.
ACS Biomater. Sci. Eng. 2021; 7: 2880-2899
Hydrogels: the next generation body materials for microfluidic chips?.
Small. 2020; 2003797: 1-26
3D bioprinting of hepatoma cells and application with microfluidics for pharmacodynamic test of metuzumab.
Biofabrication. 2019; 11: 34102
Ultrastructure of blood and lymphatic vascular networks in three-dimensional cultured tissues fabricated by extracellular matrix nanofilm-based cell accumulation technique.
Microscopy. 2014; 63: 219-226
In vitro 3D blood/lymph-vascularized human stromal tissues for preclinical assays of cancer metastasis.
Biomaterials. 2018; 179: 144-155
Investigating lymphangiogenesis in a sacrificially bioprinted volumetric model of breast tumor tissue.
Methods. 2021; 190: 72-79
A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy.
Nat. Biomed. Eng. 2019; 3: 509-519
Multiplexed drug testing of tumor slices using a microfluidic platform.
NPJ Precis. Oncol. 2020; 4: 1-15
Parallel microfluidic chemosensitivity testing on individual slice cultures.
Lab Chip. 2014; 14: 4540-4551
Microfluidic integration of regeneratable electrochemical affinity-based biosensors for continual monitoring of organ-on-a-chip devices.
Nat. Protoc. 2021; 16: 2564-2593
Immunocompetent cancer-on-chip models to assess immuno-oncology therapy.
Adv. Drug Deliv. Rev. 2021; 173: 281-305
Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice.
Exp. Mol. Med. 2018; 50: 1-9
The predictive link between matrix and metastasis.
Curr. Opin. Chem. Eng. 2016; 11: 85-93
Organ-specific metastases.
Nat. Biomed. Eng. 2018; 2: 347-348
A microfluidic system for the investigation of tumor cell extravasation.
Bioengineering. 2018; 5: 1-20
Microfluidic 3D cell culture: from tools to tissue models.
Curr. Opin. Biotechnol. 2015; 35: 118-126
A novel tumor-immune microenvironment (TIME)-on-chip mimics three dimensional neutrophil-tumor dynamics and neutrophil extracellalar traps (NETs)-mediated collective tumor invasion.
Biofabrication. 2021; 13035029
Engineering a novel 3D printed vascularized tissue model for investigating breast cancer metastasis to bone.
Adv. Healthc. Mater. 2020; 91900924
3D immunocompetent organ-on-a-chip models.
Small Methods. 2020; 42000235
Role of tumor microenvironment in tumorigenesis.
J. Cancer. 2017; 8: 761-773
Targeting pancreatic stellate cells in cancer.
Trends Cancer. 2019; 5: 128-142
Biological heterogeneity and versatility of cancer-associated fibroblasts in the tumor microenvironment.
Oncogene. 2019; 38: 4887-4901
The impact of cancer-associated fibroblasts on major hallmarks of pancreatic cancer.
Theranostics. 2018; 8: 5072-5087
Metabolic relationship between cancer- associated fibroblasts and cancer cells.
Adv. Exp. Med. Biol. 2018; 1063: 149-165
Cancer-associated fibroblasts modulate growth factor signaling and extracellular matrix remodeling to regulate tumor metastasis.
Biochem. Soc. Trans. 2017; 45: 229-236
Understanding the immune landscape and tumor microenvironment of pancreatic cancer to improve immunotherapy.
Mol. Carcinog. 2020; 59: 775-782
Fibroblasts fuel immune escape in the tumor microenvironment.
Trends Cancer. 2019; 5: 704-723
The role of collagen in cancer: from bench to bedside.
J. Transl. Med. 2019; 17: 309
CAF subpopulations: a new reservoir of stromal targets in pancreatic cancer.
Trends Cancer. 2019; 5: 724-741
A microvascularized tumor-mimetic platform for assessing anti-cancer drug efficacy.
Sci. Rep. 2018; 8: 1-15
3D bioprinting of functional tissue models for personalized drug screening and in vitro disease modeling.
Adv. Drug Deliv. Rev. 2018; 132: 235-251
Three dimensional in vitro models of cancer: bioprinting multilineage glioblastoma models.
Adv. Biol. Regul. 2020; 75100658
Bioprinting of in vitro tumor models for personalized cancer treatment: a review.
Biofabrication. 2020; 12: 42001
Molecular mechanisms of lymphangiogenesis in development and cancer.
Int. J. Dev. Biol. 2011; 55: 483-494
Biofabrication: reappraising the definition of an evolving field.
Biofabrication. 2016; 8: 13001
Bioprinting: from tissue and organ development to in vitro models.
Chem. Rev. 2020; 120: 10547-10607
3D bioprinting: from benches to translational applications.
Small. 2019; 151805510
Biofabrication strategies for 3D in vitro models and regenerative medicine.
Nat. Rev. Mater. 2018; 3: 21-37
3D bioprinting of tumor models for cancer research.
ACS Appl. Bio Mater. 2020; 3: 5552-5573
Advances in 3D bioprinting for the biofabrication of tumor models.
Bioprinting. 2021; 21e00120
Recent trends in decellularized extracellular matrix bioinks for 3D printing: an updated review.
Int. J. Mol. Sci. 2019; 20: 4628
Chemically modified biopolymers for the formation of biomedical hydrogels.
Chem. Rev. 2020; ()
Trends in double networks as bioprintable and injectable hydrogel scaffolds for tissue regeneration.
ACS Biomater. Sci. Eng. 2021; ()
Nanocomposite bioink exploits dynamic covalent bonds between nanoparticles and polysaccharides for precision bioprinting.
Biofabrication. 2020; 12: 25025
Instant gelation system as self-healable and printable 3D cell culture bioink based on dynamic covalent chemistry.
ACS Appl. Mater. Interfaces. 2020; 12: 38918-38924
3D printing in suspension baths: keeping the promises of bioprinting afloat.
Trends Biotechnol. 2020; 38: 584-593
FRESH 3D bioprinting a full-size model of the human heart.
ACS Biomater. Sci. Eng. 2020; 6: 6453-6459
Three-dimensional printing of complex biological structures by freeform reversible embedding of suspended hydrogels.
Sci. Adv. 2015; 1e1500758
Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model.
Oncoimmunology. 2019; 81553477
3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade.
Lab Chip. 2018; 18: 3129-3143
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