Friedman, J. M. Causes and control of excess body fat. Thiên nhiên 459, 340 tầm 342 (2009).
Ng, M. et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Dao mổ 384, 766 tầm 781 (2014).
Afshin, A. et al. Health effects of overweight and obesity in 195 countries over 25 years. Tiếng Anh J. Med. 377, 13 tầm 27 (2017).
Van Gaal, L. F., Mertens, I. L. & De Block, C. E. Mechanisms linking obesity with cardiovascular disease. Thiên nhiên 444, 875 tầm 880 (2006).
Kahn, S. E., Hull, R. L. & Utzschneider, K. M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Thiên nhiên 444, 840 tầm 846 (2006).
Henao-Mejia, J. et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Thiên nhiên 482, 179 tầm 185 (2012).
Olson, O. C., Quail, D. F. & Joyce, J. A. Obesity and the tumor microenvironment. Khoa học 358, 1130 tầm 1131 (2017).
Heymsfield, S. B. & Wadden, T. A. Mechanisms, pathophysiology, and management of obesity. Tiếng Anh J. Med. 376, 254 tầm 266 (2017).
Vetter, M. L., Faulconbridge, L. F., Webb, V. L. & Wadden, T. A. Behavioral and pharmacologic therapies for obesity. Nat. Rev. Endocrinol. 6, 578 tầm 588 (2010).
Agostinis, P. et al. Photodynamic therapy of cancer: an update. Ca. Cancer J. Clin. 61, 250 tầm 281 (2011).
Zhou, Z., Song, J., Nie, L. & Chen, X. Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy. Hóa. Sóc. Rev 45, 6597 tầm 6626 (2016).
Chilakamarthi, U. & Giribabu, L. Photodynamic therapy: past, present and future. Chem. Rec. 17, 775 tầm 802 (2017).
Wanner, M. et al. Use of photodynamic therapy and sterile water to target adipose tissue. Dermatologic Surg. 41, 803 tầm 811 (2015).
Peirce, V., Carobbio, S. & Vidal-Puig, A. The different shades of fat. Thiên nhiên 510, 76 tầm 83 (2014).
Liu, Y., Nie, L. & Chen, X. Photoacoustic molecular imaging: from multiscale biomedical applications towards early-stage theranostics. Xu hướng Biotechnol. 34, 420 tầm 433 (2016).
Wang, LV & Hu, S. Chụp cắt lớp quang âm: chụp ảnh in vivo từ các bào quan đến các cơ quan. Khoa học 335, 1458 tầm 1462 (2012).
Wang, L. V. & Yao, J. A practical guide to photoacoustic tomography in the life sciences. Nat. Phương pháp 13, 627 tầm 638 (2016).
Valluru, K. S., Wilson, K. E. & Willmann, J. K. Photoacoustic imaging in oncology: translational preclinical and early clinical experience. Radiology 280, 332 tầm 349 (2016).
Reber, J. et al. Non-invasive measurement of brown fat metabolism based on optoacoustic imaging of hemoglobin gradients. Tế bào Metab. 27, 689 tầm 701 (2018).
Lovell, J. F., Liu, T. W. B., Chen, J. & Zheng, G. Activatable photosensitizers for imaging and therapy. Hóa. Rev 110, 2839 tầm 2857 (2010).
Calixto, G. M. F. et al. Nanotechnology-based drug delivery systems for photodynamic therapy of cancer: a review. phân tử 21, 342 (2016).
Ho, C. J. H. et al. Multifunctional photosensitizer-based contrast agents for photoacoustic imaging. Khoa học Dân biểu 4, 5342 (2014).
Bartelt, A. & Heeren, J. Adipose tissue browning and metabolic health. Nat. Rev. Endocrinol. 10, 24 tầm 36 (2014).
Mannerås-Holm, L. & Krook, A. Targeting adipose tissue angiogenesis to enhance insulin sensitivity. Bệnh đái tháo đường 55, 2562 tầm 2564 (2012).
Festuccia, W. T., Laplante, M., Berthiaume, M., Gélinas, Y. & Deshaies, Y. PPARγ agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control. Bệnh đái tháo đường 49, 2427 tầm 2436 (2006).
Clarke, B. E. et al. Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein. Thiên nhiên 330, 381 tầm 384 (1987).
Ji, M. et al. Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau.P301S mouse model of Alzheimer’s disease and frontotemporal dementia. Alzheimers Res. Ther. 10, 55 (2018).
Lu, Y. et al. Assessing sequence plasticity of a virus-like nanoparticle by evolution toward a versatile scaffold for vaccines and drug delivery. Proc. Học viện Natl. Khoa học Hoa Kỳ 112, 12360 tầm 12365 (2015).
Kolonin, M. G., Saha, P. K., Chan, L., Pasqualini, R. & Arap, W. Reversal of obesity by targeted ablation of adipose tissue. Nat. Med. 10, 625 tầm 632 (2004).
Won, Y. W. et al. Oligopeptide complex for targeted non-viral gene delivery to adipocytes. Nat. Vật chất. 13, 1157 tầm 1164 (2014).
Shan, W. et al. Improved stable indocyanine green (ICG)-mediated cancer optotheranostics with naturalized hepatitis B core particles. Tư vấn. Vật chất. 30, 1707567 (2018).
Kershaw, E. E. et al. PPARγ regulates adipose triglyceride lipase in adipocytes in vitro and in vivo. Là. J. Physiol. Nội tiết. Metab. 293, 1736 tầm 1745 (2007).
Tang, J. et al. Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity. Nội bộ J. Obes. 43, 1269 tầm 1280 (2019).
Thiam, A. R., Farese, R. V. J. & Walther, T. C. The biophysics and cell biology of lipid droplets. Nat. Linh mục Mol. Biol tế bào. 14, 775 tầm 786 (2013).
Zhang, C. et al. A cystine knot peptide targeting integrin αvβ6 for photoacoustic and fluorescence imaging of tumors in living subjects. J. Hạt nhân. Med. 57, 1629 tầm 1634 (2016).
Crandall, D. L., Goldstein, B. M., Huggins, F. & Cervoni, P. Adipocyte blood flow: influence of age, anatomic location, and dietary manipulation. Là. J. Physiol. Regul. Tích phân. Comp. Vật lý trị liệu. 247, R46 – R51 (1984).
Wang, P. et al. Absence of an adipogenic effect of rosiglitazone on mature 3T3-L1 adipocytes: increase of lipid catabolism and reduction of adipokine expression. Bệnh đái tháo đường 50, 654 tầm 665 (2007).
Li, G., Gong, J., Lei, H., Liu, J. & Xu, X. Z. S. Promotion of behavior and neuronal function by reactive oxygen species in C. Elegans. Nat. Cộng đồng. 7, 13234 (2016).
Zou, Z., Chang, H., Li, H. & Wang, S. Induction of reactive oxygen species: an emerging approach for cancer therapy. Apoptosis 22, 1321 tầm 1335 (2017).
Yaribeygi, H., Farrokhi, F. R., Butler, A. E. & Sahebkar, A. Insulin resistance: review of the underlying molecular mechanisms. J. Sinh lý tế bào. 234, 8152 tầm 8161 (2019).
Krawczyk, S. A., Haller, J. F., Ferrante, T., Zoeller, R. A. & Corkey, B. E. Reactive oxygen species facilitate translocation of hormone sensitive lipase to the lipid droplet during lipolysis in human differentiated adipocytes. PLoS ONE 7, e34904 (2012).
Straus, D. S. & Glass, C. K. Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms. Xu hướng Immunol. 28, 551 tầm 558 (2007).
Bensinger, S. J. & Tontonoz, P. Integration of metabolism and inflammation by lipid-activated nuclear receptors. Thiên nhiên 454, 470 tầm 477 (2008).
Polvani, S., Tarocchi, M. & Galli, A. PPAR and oxidative stress: Con(β) catenating NRF2 and FOXO. PPAR Res 2012, 641087 (2012).
Xue, Y. et al. Hypoxia-independent angiogenesis in adipose tissues during cold acclimation. Tế bào Metab. 9, 99 tầm 109 (2009).
Reuter, S., Gupta, S. C., Chaturvedi, M. M. & Aggarwal, B. B. Oxidative stress, inflammation, and cancer: how are they linked? Radic tự do. sinh học. y tế. 49, 1603 tầm 1616 (2010).
Sackmann-Sala, L., Berryman, D. E., Munn, R. D., Lubbers, E. R. & Kopchick, J. J. Heterogeneity among white adipose tissue depots in male C57BL/6J mice. Bệnh béo phì 20, 101 tầm 111 (2012).
Nathan, D. M. Rosiglitazone and cardiotoxicity—weighing the evidence. Tiếng Anh J. Med. 357, 64 tầm 66 (2007).
Ratziu, V. et al. Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial. Hepatology 51, 445 tầm 453 (2010).
Moreno, A. M. et al. Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy. Nat. Sinh học. Anh 3, 806 tầm 816 (2019).
Wu, Z. et al. In vivo dual-scale photoacoustic surveillance and assessment of burn healing. Sinh học. Opt. Thể hiện 10, 3425 tầm 3433 (2019).
Matthews, D. R. et al. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Bệnh đái tháo đường 28, 412 tầm 419 (1985).