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NANOBIOTIX to Host Virtual KOL Event Discussing Potential First-in-Class Radioenhancer NBTXR3 In Immunotherapy on June 11, 2021




NANOBIOTIX (Paris:NANO) (NASDAQ:NBTX) (Euronext : NANO –– NASDAQ: NBTX – the ‘‘Company’’), a late-clinical stage biotechnology company pioneering physics-based approaches to expand treatment possibilities for patients with cancer, today announced that it will host a virtual KOL event for analysts, investors, and the scientific community on Friday, June 11, 2021 at 8AM ET / 2PM CET. The event will feature several key opinion leaders, including current study investigators.

The Nanobiotix KOL event will provide an in-depth review of the immunotherapy data presented at the 2021 Annual Meeting of American Society for Clinical Oncology (ASCO) along with clinical perspectives on the implications of potential first-in-class radioenhancer NBTXR3 across the oncology landscape.

Registration for the event is now open on the events section of the Company’s website. A live webcast of the discussion and an archived recording will be available on the events section as well.

Nanobiotix Virtual KOL Event Program

Can NBTXR3 Turn Anti-PD-1 Non-responders into Responders and Deepen Response in Naïve Patients?


  • Opening Remarks (8:00AM ET / 2:00PM CET)
    • Presented by Jeffrey Bockman, PhD, EVP and Oncology Practice Head, Cello Health BioConsulting
  • NBTXR3 Mode of Action (8:05AM ET / 2:05PM CET)
    • Presented by Laurent Levy, PhD, co-founder and CEO, Nanobiotix
  • Overview of the Treatment Landscape: Promise and Limitations of Immunotherapy, and Rationale for Combination-based Approaches (8:10AM ET / 2:10PM CET)
    • Presented by Jared Weiss, MD, Associate Professor of Medicine, Division of Oncology, University of North Carolina Lineberger Comprehensive Cancer Center
  • Nanobiotix Study 1100 Safety and Efficacy Data Update (8:20AM ET / 2:20PM CET)
    • Presented by Tanguy Seiwert, MD, Assistant Professor of Oncology, Director, Head and Neck Cancer Oncology Disease Group, Johns Hopkins Medicine and Colette Shen, MD, PhD, Assistant Professor, Radiation Oncology, University of North Carolina Lineberger Comprehensive Cancer Center
  • NBTXR3 as a Potential Combination-agnostic Product, Rationale, and Future Opportunity (8:40AM ET / 2:20PM CET)
    • Presented by James Welsh, MD, Associate Professor, Department of Radiation Oncology, University of Texas MD Anderson Cancer Center
  • Discussion and Q&A, Implications of Study 1100 in Head and Neck Cancer and Beyond (8:50AM ET / 2:50PM CET)
    • Panel Discussion Moderated by Jeffrey Bockman
  • Summary Close (9:10AM ET / 3:10PM CET)
    • Presented by Jeffrey Bockman



Nanobiotix is a late-stage clinical biotechnology company pioneering disruptive, physics-based therapeutic approaches to revolutionize treatment outcomes for millions of patients; supported by people committed to making a difference for humanity. The company’s philosophy is rooted in the concept of pushing past the boundaries of what is known to expand possibilities for human life.

Incorporated in 2003, Nanobiotix is headquartered in Paris, France. The company also has subsidiaries in Cambridge, Massachusetts (United States), France, Spain, and Germany. Nanobiotix has been listed on Euronext: Paris since 2012 and on the Nasdaq Global Select Market in New York City since December 2020.

Nanobiotix is the owner of more than 30 umbrella patents associated with three (3) nanotechnology platforms with applications in 1) oncology; 2) bioavailability and biodistribution; and 3) disorders of the central nervous system. The Company’s resources are primarily devoted to the development of its lead product candidate–NBTXR3—which is the product of its proprietary oncology platform and has already achieved market authorization in Europe for the treatment of patients with soft tissue sarcoma under the brand name Hensify®.

For more information about Nanobiotix, visit us at or follow us on LinkedIn and Twitter


This press release contains certain “forward-looking” statements within the meaning of applicable securities laws, including the Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by words such as “at this time,” “anticipate,” “believe,” “expect,” “intend,” “on track,” “plan,” “scheduled,” and “will,” or the negative of these and similar expressions. These forward-looking statements, which are based on our management’s current expectations and assumptions and on information currently available to management, include statements about the timing and progress of clinical trials, the timing of our presentation of data, the results of our preclinical and clinical studies and their potential implications, the development and commercialization of NBTXR3, and the execution of the Company’s development and commercialization strategy. Such forward-looking statements are made in light of information currently available to us and based on assumptions that Nanobiotix considers to be reasonable. However, these forward-looking statements are subject to numerous risks and uncertainties, including with respect to the risk that subsequent studies and ongoing or future clinical trials may not generate favorable data notwithstanding positive preclinical or early clinical result and the risks associated with the evolving nature of the duration and severity of the COVID-19 pandemic and governmental and regulatory measures implemented in response to it. Furthermore, many other important factors, including those described in Annual Report on Form 20-F filed with the U.S. Securities and Exchange Commission on April 7, 2021 under “Item 3.D. Risk Factors” and those set forth in the universal registration document of Nanobiotix filed with the French Financial Markets Authority (Autorité des marchés financiers) under number D.21-0272 on April 7, 2021 (a copy of which is available on, as well as other known and unknown risks and uncertainties may adversely affect such forward-looking statements and cause our actual results, performance or achievements to be materially different from those expressed or implied by the forward-looking statements. Except as required by law, we assume no obligation to update these forward-looking statements publicly, or to update the reasons why actual results could differ materially from those anticipated in the forward-looking statements, even if new information becomes available in the future.


Nanobiotix Communications
Brandon Owens
VP, Communications
+1 (617) 852-4835

Nanobiotix Investor Relations
Kate McNeil
SVP, Investor Relations
+1 (609) 678-7388

Media Relations
France – Ulysse Communication
Pierre-Louis Germain

+ 33 (0) 6 64 79 97 51

US – Porter Novelli
Stefanie Tuck

+1 (917) 390-1394

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Artificial Intelligence

Extra Crunch roundup: TC Mobility recaps, Nubank EC-1, farewell to browser cookies



What, exactly, are investors looking for?

Early-stage founders, usually first-timers, often tie themselves in knots as they try to project the qualities they hope investors are seeking. In reality, few entrepreneurs have the acting skills required to convince someone that they’re patient, dedicated or hard-working.

Johan Brenner, general partner at Creandum, was an early backer of Klarna, Spotify and several other European startups. Over the last two decades, he’s identified five key traits shared by people who create billion-dollar companies.

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“A true unicorn founder doesn’t need to have all of those capabilities on Day One,” says Brenner, “but they should already be thinking big while executing small and demonstrating that they understand how to scale a company.”

Drawing from observations gleaned from working with founders like Spotify’s Daniel Ek, Sebastian Siemiatkowski from Klarna, and iZettle’s Jacob de Geer and Magnus Nilsson, Brenner explains where “VC FOMO” comes from and how it drives dealmaking.

We’re running a series of posts that recap conversations from last week’s virtual TC Mobility conference, including an interview with Refraction AI’s Matthew Johnson, a look at how autonomous delivery startups are navigating the regulatory and competitive landscape, and much more. There are many more recaps to come; click here to find them all.

Thanks very much for reading Extra Crunch!

Walter Thompson
Senior Editor, TechCrunch

How contrarian hires and a pitch deck started Nubank’s $30 billion fintech empire

Image Credits: Nigel Sussman

Founded in 2013 and based in São Paulo, Brazil, Nubank serves more than 34 million customers, making it Latin America’s largest neobank.

Reporter Marcella McCarthy spoke to CEO David Velez to learn about his efforts to connect with consumers and overcome entrenched opposition from established players who were friendly with regulators.

In the first of a series of stories for Nubank’s EC-1, she interviewed Velez about his early fundraising efforts. For a balanced perspective, she also spoke to early Nubank investors at Sequoia and Kaszek Ventures, Latin America’s largest venture fund, to find out why they funded the startup while it was still pre-product.

“There are people you come across in life that within the first hour of meeting with them, you know you want to work with them,” said Doug Leone, a global managing partner at Sequoia who’d recruited Velez after he graduated from grad school at Stanford.

Marcella also interviewed members of Nubank’s founding team to better understand why they decided to take a chance on a startup that faced such long odds of success.

“I left banking to make a fifth of my salary, and back then, about $5,000 in equity,” said Vitor Olivier, Nubank’s VP of operations and platforms.

“Financially, it didn’t really make sense, so I really had to believe that it was really going to work, and that it would be big.”

Despite flat growth, ride-hailing colossus Didi’s US IPO could reach $70B

Image Credits: Didi

In his last dispatch before a week’s vacation, Alex Wilhelm waded through the numbers in Didi’s SEC filing. The big takeaways?

“While Didi managed an impressive GTV recovery in China, its aggregate numbers are flatter, and recent quarterly trends are not incredibly attractive,” he writes.

However, “Didi is not as unprofitable as we might have anticipated. That’s a nice surprise. But the company’s regular business has never made money, and it’s losing more lately than historically, which is also pretty rough.”

What’s driving the rise of robotaxis in China with AutoX, Momenta and WeRide

AutoX, Momenta and WeRide took the stage at TC Sessions: Mobility 2021 to discuss the state of robotaxi startups in China and their relationships with local governments in the country.

They also talked about overseas expansion — a common trajectory for China’s top autonomous vehicle startups — and shed light on the challenges and opportunities for foreign AV companies eyeing the massive Chinese market.

The air taxi market prepares to take flight

Image Credits: Bryce Durbin

“As in any disruptive industry, the forecast may be cloudier than the rosy picture painted by passionate founders and investors,” Aria Alamalhodaei writes. “A quick peek at comments and posts on LinkedIn reveals squabbles among industry insiders and analysts about when this emerging technology will truly take off and which companies will come out ahead.”

But while some electric vertical take-off and landing (eVTOL) companies have no revenue yet to speak of — and may not for the foreseeable future — valuations are skyrocketing.

“Electric air mobility is gaining elevation,” she writes. “But there’s going to be some turbulence ahead.”

The demise of browser cookies could create a Golden Age of digital marketing

Though some may say the doomsday clock is ticking toward catastrophe for digital marketing, Apple’s iOS 14.5 update, which does away with automatic opt-ins for data collection, and Google’s plan to phase out third-party cookies do not signal a death knell for digital advertisers.

“With a few changes to short-term strategy — and a longer-term plan that takes into account the fact that people are awakening to the value of their online data — advertisers can form a new type of relationship with consumers,” CTO Hunter Jensen writes in a guest column. “It can be built upon trust and open exchange of value.”

If offered the right incentives, Jensen predicts, “consumers will happily consent to data collection because advertisers will be offering them something they value in return.”

How autonomous delivery startups are navigating policy, partnerships and post-pandemic operations

Nuro second gen R2 delivery vehicle

Image Credits: Nuro

We kicked off this year’s TC Sessions: Mobility with a talk featuring three leading players in the field of autonomous delivery. Gatik co-founder and chief engineer Apeksha Kumavat, Nuro head of operations Amy Jones Satrom, and Starship Technologies co-founder and CTO Ahti Heinla joined us to discuss their companies’ unique approaches to the category.

The trio discussed government regulation on autonomous driving, partnerships with big corporations like Walmart and Domino’s, and the ongoing impact the pandemic has had on interest in the space.

Waabi’s Raquel Urtasun explains why it was the right time to launch an AV technology startup

Image Credits: Waabi via Natalia Dola

Raquel Urtasun, the former chief scientist at Uber ATG, is the founder and CEO of Waabi, an autonomous vehicle startup that came out of stealth mode last week. The Toronto-based company, which will focus on trucking, raised an impressive $83.5 million in a Series A round led by Khosla Ventures.

Urtasun joined Mobility 2021 to talk about her new venture, the challenges facing the self-driving vehicle industry and how her approach to AI can be used to advance the commercialization of AVs.

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EBA Clearing and Iberpay Introduce Interoperable Services to Handle Messages that Comply with SEPA Request to Pay Scheme



EBA Clearing and Iberpay revealed on Tuesday (June 15, 2021) that they have introduced two interoperable services to handle messages and offer functionalities that comply with the updated SEPA Request-to-Pay Scheme (SRTP) developed by the European Payments Council (EPC).

The introduction of these infrastructure services took place on Tuesday, which is actually the day of the entry of the new SEPA scheme.

EBA Clearing and Iberpay have made a considerable effort to provide this service to clients right from the launch of the scheme. They claim to be the first European infrastructure providers that are ready to provide this new feature.

Payment service providers or PSPs and other service providers complying with the updated SEPA scheme are now able to exchange SRTP messages end-to-end, within seconds and across Europe, because of the connection between real-time messaging systems of EBA Clearing and Iberpay.

This key milestone offers the missing piece to support various use-cases that may help clients who rely on instant payments.

The SEPA Request-to-Pay Scheme is the set of operating rules, messages and technical elements that lets a Payee request the initiation of a payment from a Payer prior to the exchange of the funds.

The implementation of the scheme was supported by the EPC after a call to action by the Euro Retail Payments Board (ERPB) in November 2018 to start using the request to pay capability.

Request to Pay isn’t actually a payment instrument. It’s a way to request a payment initiation (pull payment). Request to Pay services are offered 24 hours, 7 days a week. They aim to enhance the payment process by adding a message exchange, which occurs before the payment (SCT or SCT Inst) and includes:

  • A request to the Payer for a payment.
  • The acceptation or refusal of this request by the Payer.
  • The information delivered as part of this request to pay exchange, allows the Payer to identify the Payee and makes it easier for the Payee to identify and reconcile the following payment.

Request to Pay should further improve with ongoing developments and has been identified by the European Commission and the Eurosystem in their retail payments plans as having the potential to add value to the SEPA Instant Credit Transfer (SCT Inst) Scheme and to also improve the usability while supporting the adoption of instant and virtual payments.

Request to Pay may be used to support unpaid or returned direct debits, digital commerce payments, substitution of other payment instruments, public administration payments, payment of e-invoices and even at point of sale.

Juan Luis Encinas, MD at Iberpay, stated:

“Iberpay is strongly committed to playing a leading role in instant and digital payments and we believe that the launch of our Request to Pay service from the very beginning is a very important milestone for that. IBERPAY is extremely pleased to collaborate with EBA CLEARING with the aim to assure pan-European reachability for the SRTP Scheme and to better serve its users.”

Hays Littlejohn, CEO at EBA Clearing, remarked:

“We are pleased to see the Spanish community connected to our R2P Service from day one of the SRTP Scheme. IBERPAY is the first infrastructure provider extending R2P access to its user community. This supports our objective to build full pan-European reach for Request to Pay and ensure interoperability between the underlying infrastructures”.

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B9 Raises Pre-Seed Funding to Help New American Workers Get Paid



A pre-seed funding round of $1.7 million will help U.S. fintech startup B9 build its financial app that helps immigrant workers secure interest-free payroll advances.

“Immigrant communities and other marginalized groups are invisible to traditional banks,” B9 CEO Sergei Terentyev said. “They are hardworking people who deserve a full service banking option that fits the way they earn and spend.” Terentyev called the response to B9 “overwhelming” and said that “hundreds of thousands” of interested users have joined the company’s waiting list.

“In our view, access to banking services that allow families to share resources, build credit and plan for the future is an equality issue, and the early response we’ve seen demonstrates the magnitude of the demand,” Terentyev added.

B9 offers 0% APR pay advances of up to 15 days, as well as a free virtual Visa debit card, and access to both U.S. and international money transfers. The San Francisco, California-based company charges a monthly subscription fee of $4.99.

B9 will use the funding to add to its team, as well as make technology investments. The company hopes to have 100,000 customers by the end of the year with its focus on consumers who are not only underserved by traditional banks, but are also often preyed upon by predatory lenders. In addition to its early wage access feature, B9 expects to offer additional services such as merchant discounts and access to insurance.

In their funding announcement, the company underscored the size of the non-U.S. born population – more than 40 million – as well as the fact that the lion’s share of U.S. population growth – up to 80% – will come from the growth of the first- and second-generation immigrant population.

B9’s services are set up with this in mind. In addition to offering a low, monthly subscription rate, applicants only require a U.S. mailing address, social security number, or ITIN, as well as a government-issued ID from either a U.S. source or from the applicant’s country of origin. Multiple language customer service is available.

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Wise, Formerly Transferwise, to Pursue a Direct Listing on LSE as Soon as This Week: Report



Wise, formerly doing business as Transferwise, is to complete a direct listing on the London Stock Exchange (LSE) according to reports.

Wise, a global Fintech and stealth bank, is a leading provider of global transfers and payments. The site was launched in recognition of the gouging taking place when an individual attempted to exchange one currency for another. Wise is proud of its low fees and real spot rates for currency exchange.

According to a report in Reuters, pending regulatory approval, shares in Wise will float on the LSE as soon as this week or perhaps a bit later in the month.

The estimated valuation of Wise, long a Fintech unicorn, range from $6 billion to up to over $12 billion. In July 2020, it was reported that Wise raised over $300 million at a valuation of $5 billion. Wise has been a profitable operation for several years and is not necessarily in need of any additional growth capital.

Wise is said to be pursuing a dual-class share structure thus providing early investors as well as company co-founders a greater voice in how Wise will be managed and controlled.

Earlier this year, Wise announced its rebranding while sharing it had topped 10 million global users – including individuals and businesses.

Wise reports moving over £5 billion every month providing a service that is estimated to save users £3 million in bank fees every day. Customers may hold balances in over 55 different currencies and use the Wise debit card to shop and spend while abroad. Wise has also partnered with both traditional financial services firms as well as Fintechs – like Monzo and GoCardless, to integrate its services. Wise claims 14 global offices and 2400 employees.

Wise is well-positioned to provide additional bank-like services such as interest-bearing accounts. Several months back, Wise revealed its intention to pursue accounts that generate a return, starting in the UK, but has yet to announce the much-anticipated feature. Once Wise enables accounts that encourage users to hold value with the Fintech the company becomes significantly more competitive versus traditional banks.

The direct listing will be widely watched by the Fintech community as a benchmark accomplishment.

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