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Laser-induced nanobubbles safely ablate vitreous opacities in vivo

Date:

Nature Nanotechnology, Published online: 17 March 2022; doi:10.1038/s41565-022-01086-4

Vitreous opacities, which are collagen aggregates that form in the eye and cause vision impairment (eye floaters), are currently treated with invasive surgical intervention or high-energy laser photoablation. In this paper, the authors show that exposing gold nanoparticles or indocyanine green to low-energy laser pulses generates vapour nanobubbles that can disrupt collagen aggregates in the eyes of rabbit, suggesting a milder strategy for the treatment of eye floaters.

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