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CIRM invests $10 million to build California Cell and Gene Therapy Manufacturing Network

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A laboratory at UCLA’s current good manufacturing practices facility | Photo credit: Elena Zhukova

The California Institute for Regenerative Medicine (CIRM), the world’s largest institution dedicated to regenerative medicine, awarded $10 million to five facilities as part of the first phase to build a California Cell and Gene Therapy Manufacturing Network.

The awards include:

Application #  Program Title  Principal Investigator/Institution  Amount 
INFR5-14663   Laboratory for Cell and Gene Medicine: A partner in the California Cell and Gene Therapy Manufacturing Network  Steven Feldman — Stanford University  $2,000,000 
INFR5-14739    Enhancing California’s Manufacturing of Leading-Edge Cell & Gene Therapies  Dawn Ward — University of California, Los Angeles  $2,000,000 
INFR5-14756   Scalable Expansion for Stem Cell-Derived Therapies  Taby Ahsan — Beckman Research Institute of City of Hope  $1,998,174 
INFR5-14636   A comprehensive biomanufacturing center solving bottlenecks in cell and gene therapy manufacturing to accelerate new therapies for California patients  Dhruv Sareen — Cedars-Sinai Medical Center  $2,000,000 
INFR5-14719   Open Manufacturing Network for Cell and Gene Therapies  Brian Rudolph Shy — University of California, San Francisco  $1,999,933 

The statewide network is designed to overcome manufacturing bottlenecks that have delayed or stalled development and approval of regenerative medicines. 

“These awards are a critical first step in formation of the manufacturing network and will help California academic GMP manufacturing facilities raise the quality and competency of cell and gene therapy manufacturing across the state,” says CIRM Senior Director of Business Development & Alliance Management Dr. Shyam Patel. “Plus, these awards will also provide manufacturing career training opportunities for Californians, which align perfectly with CIRM’s mission.”  

Phase one of the awards will fund California non-profit GMP manufacturing facilities for two years. Each facility will support in accelerating and de-risking the path to commercialization for cell and gene therapies, advancing industry standards and quality by design, and building a diverse and highly skilled manufacturing workforce in California.  

Phase two of the awards will fund collaborative partnerships that will scale efforts from the first phase across the network. 

To learn more about CIRM’s Infrastructure programs, including future funding opportunities, visit our website.

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