Individuals who exhibit symptoms such as skin pigmentation, swelling, and ulcers are at a higher risk of suffering from kidney disease. Hence, it is best to discuss the symptoms with a nephrologist in Lahore. A reliable and competent specialist will conduct relevant tests to diagnose the illness and provide treatment accordingly. An early diagnosis can prevent the permanent damage to the vital organs and enhance the quality of life.

It is a condition in which the person suffers from symptoms that indicate hindrance in the kidney functioning due to scarring. 

The symptoms of Nephrogenic systemic fibrosis are:

• The individual can notice the swelling and tightening of the skin that causes difficulty in movement. The skin becomes thick and hard, which causes extreme discomfort.
• The patient can notice skin pigmentation, which affects their physical appearance.
• The patient feels burning and itchiness in the affected part.
• The person suffers from joint pain due to the thickness of the skin.
• The patient suffers from blisters and ulcers that may worsen with time and cause permanent scarring.
• The patient suffers from muscle weakness, which hinders their performance.
• The fibrosis can worsen with time without treatment and extend to the pleura and pericardium.

The known causes of nephrogenic systemic fibrosis are:

• Individuals with exposure to gadolinium are more likely to suffer from kidney disease, including nephrogenic systemic fibrosis.
• Individuals with high production of erythropoietin are at a high risk of suffering from nephrogenic systemic fibrosis.
• Individuals with a history of vascular surgery should remain vigilant and notice the bodily changes as they are at a high risk of suffering from nephrogenic systemic fibrosis.
• Individuals with a blood disorder are more likely to suffer from lotting that can hinder kidney function.
• Infections should be treated on time to avoid damage to the kidneys and other vital organs.

The individuals who are at a high risk of developing kidney disease are:

An individual with a kidney transplant is more likely to suffer from nephrogenic systemic fibrosis.

• People undergoing hemodialysis or peritoneal dialysis are at a higher risk of contracting infections that can lead to nephrogenic systemic fibrosis.
• People with physical injury should be vigilant and visit a doctor. An injury to the kidney can cause scarring and other complications.
• Individuals with acute kidney disease are at a higher risk of suffering from nephrogenic systemic fibrosis.

The preventative measures that help reduce the chances of suffering from nephrogenic systemic fibrosis are:

• Individuals with a prior medical condition should monitor the changes in the body to avoid kidney disease.
• People with blood disorders should remain conscious and avoid exposure to gadolinium which can lead to nephrogenic systemic fibrosis
• People noticing unusual symptoms such as skin hardening should consult the doctor for an early diagnosis.

The tests that help diagnose an individual with nephrogenic systemic fibrosis are:

• Physical Examination: The specialist will conduct a thorough physical exam to check the clusters and skin thickening to evaluate the severity of the condition. Additionally, the patient will provide information regarding other medical conditions that may have led to nephrogenic systemic fibrosis.
• Skin Biopsy: The cells of the skin will be closely examined to confirm the diagnosis.

The effective treatment plan for nephrogenic systemic fibrosis includes:

• The hemorheological agents promote blood circulation and enhance kidney functioning.
• The kinase inhibitors help deal with skin thickening and pigmentation to enhance movement and manage the symptoms of nephrogenic systemic fibrosis.
• Individuals with reduced kidney function have to undergo hemodialysis or transplant to help the patient manage the symptoms and perform well in everyday tasks.
• The ultraviolet phototherapy helps reduce skin thickening to improve body movement.

Individuals diagnosed with nephrogenic systemic fibrosis should seek a second opinion from the nephrologist in Islamabad. The specialist will provide guidance regarding the most effective and latest treatment options to improve bodily functions and avoid complications.