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Just over a year since the latest funding, 1inch raised a Series B round of funding in December 2021, led by Amber Group, for a total of $175 million. 1inch looks a bit like Yearn as a DEX aggregator.

HONG KONG, Mar 17, 2022 - (ACN Newswire) - Sisram Medical Ltd (the "Company" or "Sisram", stock code: 1696.HK; together with its subsidiaries referred as the "Group"), a global consumer wellness group, featuring a never-before-seen synergistic ecosystem of business building blocks and consumer-focused branding, ranging from medical aesthetics capital equipment, via injectables therapy, aesthetic dentistry, personal care and more, today announced its audited consolidated annual results for the year ended December 31, 2021 (the "Reporting Period").

FINANCIAL HIGHLIGHTS
-- Revenue for the year ended December 31, 2021 was US$294.3 million, increased by 81.6% as compared to the revenue for the previous year.
-- Profit for the year ended December 31, 2021 was US$32.5 million, increased by 121.5% as compared to that for the previous year.
-- Net cash flows from operating activities for the year ended December 31, 2021 was US$32.4 million, increased by 25.8% as compared to that for the previous year.
-- Significant growth in all regions, mainly in North America and APAC. Revenue in North America for the year ended December 31, 2021 was US$112.0 million, increased by 105.8% as compared to that for the previous year. Revenue in APAC for the year ended December 31, 2021 was US$85.2 million, increased by 95.3% as compared to that for the previous year.

BUSINESS HIGHLIGHTS
-- R&D investments increased by 42.3% YoY to US$15.6 million with 2 new products launched: "Alma Duo" and "Alma PrimeX".
-- Continued the development of two new business lines - (i) Copulla - a new, innovative digital dentistry service; (ii) LMNT, a personal care brand, now launching a light-based skin rejuvenation home use device.
-- The Group entered into a sub-license agreement with Fosun Industrial for the commercialization of "RT002" Injectable, the new generation of neurotoxins for medical aesthetics use. The Group's existing injectables distribution operation, registered a revenue growth of 50.1% year over year.
-- The Group entered into an investment agreement at the amount of RMB 2.6 million for the establishment of Tianjin Xingsiyi, a research & development, technical services and supply operation for silk fibroin-sodium injectables and facial implant thread products.
-- The Group has acquired the entire share capital of Shanghai Foshion Medical System to further enhance its dental business line.
-- The Group purchased the remaining 40% equity interest in its Israeli distributor, Nova Medical. Upon completion, Nova Medical is a wholly-owned subsidiary of the Company, rebranded as Alma Israel.

FINAL DIVIDEND
-- The Board has resolved to declare a final dividend of HK$0.157 (inclusive of tax) per Share for the year ended December 31, 2021.

Business Growth Projection for 2022
Based on an increase in the demand for the Company's products and the backlog of orders as of December 31, 2021, barring any unforeseen circumstances or material change in market conditions, the Group expects to record a significant growth in revenue of over 35.0% in the first half of 2022 as compared to the revenue recorded in the corresponding period in 2021.

Record results, strong subsidiaries performance, overall geographic performance uptake, continued investments in R&D and strong business development momentum In 2021, Sisram's established global sales and distribution network recorded a total revenue of US$294.3 million for the Reporting Period, representing an increase of 81.6% when compared to 2020. All regions revenue increased substantially during the Reporting Period with North America demonstrating an increase of 105.8%, Asia Pacific with an increase of 95.3%, Latin America with an increase of 76.3%, Europe with an increase of 49.7% and Middle East & Africa with an increase of 45.2%.

The gross profit increased from US$90.3 million in 2020 to US$166.9 million in 2021, representing an increase of US$76.6 million. The gross profit margin in 2021 amounted to 56.7%, representing an increase of 1% compared to 55.7% in 2020. The establishment of direct operation offices in chosen territories has enabled the Company to shorten the supply chain, increase the average selling price, gain a higher brand visibility and ensure consistency among the communications with the target clientele. During 2021, revenue derived from direct sales has surpassed revenue derived from distributors with 62.0% attributed to the former and 38.0% to the latter.

For the Reporting Period, the Group recorded an adjusted net profit of US$40.3 million representing an increase of 100.0% when compared with the corresponding period of 2020. The adjusted net profit margin for the Reporting Period was 13.7%. The net cash flow from operating activities amounted to US$32.4 million, representing an increase of 25.8% when compared to 2020.

In 2021, Sisram continued its substantial R&D efforts, with 13% of corporate employees being R&D specialists. During the Reporting Period, R&D expense increased by 42.3% to US$15.6 million from US$11.0 million for the corresponding period in 2020. During the Reporting Period, the Group launched 2 new products, "Alma Duo" and "Alma PrimeX", as well as expanded two business lines, "Copulla" - a new, innovative digital dentistry service, and "LMNT", a personal care brand, now launching a light-based skin rejuvenation home use device.

Continued Investments in Digital Transformation and Production Ramp-up
In 2021, Sisram continued the development of its digital core architecture with vast investments in Information Systems and Digitalization, encompassing traditional ERP and CRM modules, IoT solutions for professional capital equipment, marketing automation and consumer access. Over the past 3 years (2019-2021), Sisram invested more than US$6.5 million in information systems, upgrading its ERP and CRM infrastructure, migrating to cloud-based systems to serve the entire growing and diverse eco-system and implementing new digital tools for Internal organization management, external engagement mechanisms between the organization and the market and cyber security.

On the operational front, Sisram focused on addressing the pandemic effect by investing in production ramp-up to accommodate the growing global demand and improve quality performances KPI's such as FPY (First Pass Yield) and new platforms critical failure.

A Never-before-seen Synergistic Ecosystem Composed of 4 Pillars
Sisram's Wellness Group is a never-before-seen synergistic ecosystem of business building blocks and consumer-focused branding, ranging from medical aesthetics capital equipment, via injectables therapy, aesthetic dentistry, personal care and more.

As of 2021 Sisram is operating 4 business lines. The Medical Aesthetics business line, led by Alma, registered a revenue increase of 73.4%. The Injectables business line registered a revenue increase of 50.1% year over year. In 2021, Sisram integrated the activity of Shanghai Foshion Medical System into Sisram, while developing Copulla's digital dentistry service. The Personal Care business line, LMNT by Sisram Medical, is a home-use brand, immersing the essence of wellness into consumers' daily routine.

Looking forward, Mr. Liu Yi, Chairman and Executive Director of Sisram, said: "As a core member of Fosun Pharma's medical device sector, as well as the core platform of Fosun's ecosystem, we have always insisted on customer-centric philosophy and focused on technology and innovation, to continuously improve our product power and competitiveness to respond to the rapid development of the industry. In 2022, based on our charted st rategy, we will continue to promote Sisram's ecosystem, and steadily expand the product portfolio and ecological interoperability between Sisram's ecosystem, Fosun Pharma's medical device sector, and even Fosun's greater ecosystem, so as to provide customers with advanced technologies and products through the enhancement of technological applications. We will also promote the sustainable and sound development of the industry by improving clinical applications. In addition, we shall meet the market demand of the aesthetic industry through our diversified product portfolio and market strategy."

Mr. Lior Dayan, CEO of Sisram and Alma, said: "The Group's efforts during 2022 will strategically focus on expanding direct operation in strategic markets to secure market access for both professional and consumer clientele, improve digital infrastructure and tools, drive awareness and preference to our global consumer brand and leverage it to globally introduce new products and services."

About Sisram Medical Ltd
Sisram Medical Ltd (1696.HK) is a global consumer wellness group, featuring a never-before-seen synergistic ecosystem of business building blocks and consumer-focused branding, ranging from medical aesthetics capital equipment, via injectables therapy, aesthetic dentistry, personal care and more. The company is majority held by Fosun Pharma, a leading healthcare group in China. Sisram Medical successfully went public on September 19, 2017, as the first Israeli company listed on the Hong Kong Exchange Main Board.

Sisram Medical - Enhancing Quality of Life
http://www.sisram-medical.com


Copyright 2022 ACN Newswire. All rights reserved. www.acnnewswire.comSisram Medical Ltd (the "Company" or "Sisram", stock code: 1696.HK; together with its subsidiaries referred as the "Group"), a global consumer wellness group, featuring a never-before-seen synergistic ecosystem of business building blocks and consumer-focused branding

TOKYO, Mar 17, 2022 - (JCN Newswire) - NEC Corporation (TSE: 6701) has developed the world's first LHZ scheme(1) unit cell facilitating scaling up to a fully-connected architecture using superconducting parametron(2) quantum bits (qubits). NEC has succeeded in demonstrating quantum annealing operations using these qubits, which will enable high accuracy calculations. Via this achievement, NEC has made further progress toward the production of a quantum annealing machine(3), which is a type of quantum computer.
Combinational optimization is important for finding solutions to complex social issues. It aims to find the optimal solution from an enormous set of potential choices. In 1999, NEC developed a superconducting qubit for use in gate-type quantum computers. Since then, NEC has applied the technology in the research and development of a quantum annealing machine using superconducting parametron qubits that can solve combinatorial optimization problems at high speed and with great accuracy.

NEC has developed a four qubit unit cell of the LHZ scheme. This enables scaling to multiple fully-connected logical qubits utilizing superconducting parametron and circuit coupling technology. NEC has achieved a world first by successfully solving small-scale combinatorial optimization problems via quantum annealing using this new technology. In another world first, NEC has also developed a three-dimensional structure technology that efficiently connects many LHZ scheme unit cells arranged in a tile pattern with external devices.

By replicating the unit cell in a tile pattern, it is possible to easily create a structure where many qubits are logically connected to each other, whilst maintaining the features of the superconducting parametron that allow it to perform calculations with high accuracy. NEC has made progress toward the realization of a quantum annealing machine that can solve large-scale and complex combinatorial optimization problems at high speed.

NEC is working to develop a quantum annealing machine using superconducting parametrons as a project(4) commissioned by the New Energy and Industrial Technology Development Organization (NEDO). NEC is currently conducting research and development to improve the integration of superconducting parametrons in a fully connected architecture, with the aim of realizing quantum annealing machines by 2023. NEC will use these results as building blocks to further accelerate the development of quantum computers.

(1) LHZ scheme: LHZ is an abbreviation for a technique proposed by Lechner, Hauke and Zoller. As the number of qubits increases, it becomes difficult in hardware to directly connect each qubit to each of the other qubits. To solve this problem, ParityQC proposed with LHZ a transformation that enables fully connected qubits to be obtained using qubits that are physically connected to only their nearest neighbours. A unit cell, composed of four qubits and a central coupling circuit connecting them can be replicated using a tile-like pattern.
About ParityQC: https://parityqc.com/
(2) Superconducting parametron: A superconducting resonant circuit composed of Josephson junctions and capacitors which oscillates with different phases and can be used as a qubit. The lifetime of the qubit (which determines the upper limit of the time for which high-speed operation is possible) is an order of magnitude longer than that of magnetic flux qubits. It is expected that calculations performed within a fixed time period will have improved accuracy.
(3) Quantum Annealing Machine: A computer that exploits the laws of quantum mechanics to search for the minimum energy state of a cost function. The minimum energy state corresponds to the solution of the combinatorial optimization problem. The smallest unit to be calculated is a qubit. As the number of qubits increases and the connectivity between the qubits increases, larger and more complex combinatorial optimization problems can be solved.
(4) Project for Innovative AI Chip and Next-Generation Computing Technology Development
https://www.nedo.go.jp/english/activities/activities_ZZJP_100123.html

About NEC Corporation

NEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of "Orchestrating a brighter world." NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential. For more information, visit NEC at https://www.nec.com.


Copyright 2022 JCN Newswire. All rights reserved. www.jcnnewswire.comNEC Corporation (TSE: 6701) has developed the world's first LHZ scheme unit cell facilitating scaling up to a fully-connected architecture using superconducting parametron quantum bits (qubits).

MOBILE, Ala.–(BUSINESS WIRE)–American HealthTech (AHT), a wholly owned subsidiary of CPSI (NASDAQ: CPSI), and a leading provider of electronic health records (EHR) for the post-acute and senior living markets, today announced two clients have chosen to expand their partnerships with AHT. As long-standing members of the post-acute industry, each client recognizes the need for a […]

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Conference Call and Webcast to be Held at 8:00 A.M. EDT/2:00 P.M CET on March 31, 2022 PARIS & CAMBRIDGE, Mass.–(BUSINESS WIRE)–NANOBIOTIX (Euronext: NANO – NASDAQ: NBTX – the ‘‘Company’’)  (Paris:NANO) (NASDAQ:NBTX), a late-stage clinical biotechnology company pioneering physics-based approaches to expand treatment possibilities for patients with cancer, today announces that it will report its […]

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This is a post co-written with Bernard Paques, CTO of Storm Reply, and Karl Herkt, Senior Strategist at Dassault Systèmes 3DExcite. While computer vision can be crucial to industrial maintenance, manufacturing, logistics, and consumer applications, its adoption is limited by the manual creation of training datasets. The creation of labeled pictures in an industrial context […]