Hersenschuddingen zijn een wijdverbreid letsel in de Nationale voetbal competitie (NFL)met 187 hersenschudding gemeld in 2021 (blessures veroorzaakt door een impact op het hoofd, de nek of het lichaam die de de functie van de hersenen). Symptomen van een hersenschudding kunnen zijn hoofdpijn, slaapproblemen, evenwichtsproblemen, veranderingen in geheugenfuncties en andere gebieden van disfunctie.

Sustaining another concussion while still recovering from a previous concussion can result in delayed recovery and, in some cases, a life-threatening condition called "Second Impact Syndroom". A typical adult concussion patient can expect to see recovery within ten to fourteen (10 - 14) dagen, hoewel het herstel in sommige gevallen langer kan duren.

Voor een NFL-speler, het nemen van twee (2) weken vrij is geen spannend vooruitzicht. veertien (14) days off could represent missing multiple games, and practices, and possibly losing a spot on the field. If symptoms continue past the fourteen (14) day mark, these career risks can be compounded, creating strong incentives for players to get back on the field. The focus on cannabinoids came on the heels of an announcement by Major League-honkbal (MLB) that cannabis will no longer be on its list of banned substances and the NFL may be following suit soon.

Team owners have already approved a proposed collective bargaining agreement with players that would protect them from facing game suspension for testing positive for cannabis and will implement changes to testing protocols. One thing is certain doctors across the country are in agreement that NFL players are at increased risk for Chronische traumatische encefalopathie (CTE) nadat een baanbrekend rapport over het onderwerp was gepubliceerd in de Tijdschrift van de American Medical Association.

In de grootste studie in zijn soort en een samenwerking tussen de Amerikaanse ministerie van Veteranenzaken en CTE Center van de universiteit van Boston, onderzochten onderzoekers de hersenen van overleden professionele, semi-professionele, universiteits- en middelbare schoolvoetballers. Van de 111 onderzochte NFL-spelersbreinen waren er 110 (99%) showed positive CTE pathology and the authors noted that accumulations of amyloid-β, α-synuclein, and TDP-43 were common in the brains of cases with severe CTE pathology.

Traumatisch hersenletsel (TBI)

As former and current NFL players urge the league to allow cannabis to be used as a potential treatment for pain management and head trauma, research is getting a boost as major grants recently have been awarded to Fytomedicines and Medical Cannabis Institute van Harvard University, evenals anderen.

Daarnaast hebben onderzoekers van Farmacologie aan de Lewis Katz School of Medicine van Temple University in Philadelphia, are leading a research lab exploring the effects of cannabis on pain in animal studies. Currently, research results in animal models of pain, stroke, and Traumatic Brain Injury (TBI) blijven ons enthousiast maken over het potentieel voor Cannabidiol (CBD) om hersenontsteking en gerelateerde gedragsgevolgen zoals pijn en cognitieve stoornissen te verlichten.

Given these promising results and the relative safety of CBD, what is greatly needed now are trials in patients, including athletes, to determine how our laboratory results will translate to people. Mounting evidence from other animal studies suggests that CBD can act as a neuroprotective factor, thereby preventing damage to the brain.

Japanse onderzoekers found that stroke damage was lessened in mice who were treated with CBD. Specifically, the authors hypothesized that the neuroprotective effect of cannabidiol may be related to increased blood flow through the serotonerge serotonine 5-hydroxytriptamine1A-receptor. Despite cannabis’ increasing legality in the United States and its promising medical qualities, the NFL still prohibits its use.

Echter, in de afgelopen jaren, met onderhandelingen door de NFL Players Association (NFLPA), heeft de NFL haar standpunt over cannabis verzacht. De NFL is overeengekomen om een ​​miljoen dollar ($1,000,000) to research cannabis as a pain-relieving medication. In February 2022, the NFL announced that they awarded their research budget to two (2) onderzoekslaboratoria:

1. Een lab is aan de Universiteit van Regina in Canada, which is studying the use of cannabinoids not only for post-concussion treatment but also for concussion prevention. The research is attempting to determine the optimal form and dosage of CBD and THC to reduce pain and treat injuries.
2. Het andere door het laboratorium toegekende financiering is aan de University of California San Diego, which is also assessing the therapeutic efficacy of THC and CBD, both used alone and in conjunction.

The NFL has also eased its testing protocol by reducing the testing frequency, raising the threshold of THC in a player’s system to constitute a positive test, and reducing the penalties for testing positive for cannabis use. Although cannabis and cannabinoids have promising medical value, there are potential downsides, and their use should be further researched. We’ll continue to follow emerging research showing that professional athletes who experience a concussion, acute pain, and chronic pain may benefit from cannabinoids.

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• Bron: https://greencultured.co/role-of-cannabinoids-in-brain-health-of-nfl-players/