A pair of researchers at the University of California, Riverside, has used machine learning to understand what a chemical smells like — a research breakthrough with potential applications in the food flavor and fragrance industries.
“We now can use artificial intelligence to predict how any chemical is going to smell to humans,” said Anandasankar Ray, a professor of molecular, cell and systems biology, and the senior author of the study that appears in iScience. “Chemicals that are toxic or harsh in, say, flavors, cosmetics, or household products can be replaced with natural, softer, and safer chemicals.”
Humans sense odors when some of their nearly 400 odorant receptors, or ORs, are activated in the nose. Each OR is activated by a unique set of chemicals; together, the large OR family can detect a vast chemical space. A key question in olfaction is how the receptors contribute to different perceptual qualities or percepts.
“We tried to model human olfactory percepts using chemical informatics and machine learning,” Ray said. “The power of machine learning is that it is able to evaluate a large number of chemical features and learn what makes a chemical smell like, say, a lemon or a rose or something else. The machine learning algorithm can eventually predict how a new chemical will smell even though we may initially not know if it smells like a lemon or a rose.”
According to Ray, digitizing predictions of how chemicals smell creates a new way of scientifically prioritizing what chemicals can be used in the food, flavor, and fragrance industries.
“It allows us to rapidly find chemicals that have a novel combination of smells,” he said. “The technology can help us discover new chemicals that could replace existing ones that are becoming rare, for example, or which are very expensive. It gives us a vast palette of compounds that we can mix and match for any olfactory application. For example, you can now make a mosquito repellent that works on mosquitoes but is pleasant smelling to humans.”
The researchers first developed a method for a computer to learn chemical features that activate known human odorant receptors. They then screened roughly half a million compounds for new ligands — molecules that bind to receptors — for 34 odorant receptors. Next, they focused on whether the algorithm that could estimate odorant receptor activity could also predict diverse perceptual qualities of odorants.
“Computers might help us better understand human perceptual coding, which appears, in part, to be based on combinations of differently activated ORs,” said Joel Kowalewski, a student in the Neuroscience Graduate Program working with Ray and the first author of the research paper. “We used hundreds of chemicals that human volunteers previously evaluated, selected ORs that best predicted percepts on a portion of chemicals, and tested that these ORs were also predictive of new chemicals.”
Ray and Kowalewski showed the activity of ORs successfully predicted 146 different percepts of chemicals. To their surprise, few rather than all ORs were needed to predict some of these percepts. Since they could not record activity from sensory neurons in humans, they tested this further in the fruit fly (Drosophila melanogaster) and observed a similar result when predicting the fly’s attraction or aversion to different odorants.
“If predictions are successful with less information, the task of decoding odor perception would then become easier for a computer,” Kowalewski said.
Ray explained that many items available to consumers use volatile chemicals to make themselves appealing. About 80% of what is considered flavor in food actually stems from the odors that affect smell. Fragrances for perfuming cosmetics, cleaning products, and other household goods play an important role in consumer behavior.
“Our digital approach using machine learning could open up many opportunities in the food, flavor, and fragrance industries,” he said. “We now have an unprecedented ability to find ligands and new flavors and fragrances. Using our computational approach, we can intelligently design volatile chemicals that smell desirable for use and also predict ligands for the 34 human ORs.”
The study was partially funded by UCR and the National Science Foundation.
MOHAWK INDUSTRIES INVESTIGATION INITIATED BY FORMER LOUISIANA ATTORNEY GENERAL: Kahn Swick & Foti, LLC Investigates the Officers and Directors of Mohawk Industries, Inc. – MHK
NEW ORLEANS, Sept. 4, 2020 /PRNewswire/ — Former Attorney General of Louisiana, Charles C. Foti, Jr., Esq., a partner at the law firm of Kahn Swick & Foti, LLC (“KSF”), announces that KSF has commenced an investigation into Mohawk Industries, Inc. (NYSE: MHK).
On July 25, 2019, after a series of prior negative financial revelations, the Company disclosed that sales for its Flooring NA segment were down 7% due to “lower demand” for certain products resulting in excess inventory that had impacted its sales and margins.
Thereafter, the Company and certain of its executives were sued in a securities class action lawsuit, charging them with failing to disclose material information during the Class Period regarding improper revenue recognition, demand and inventory levels as well as fraudulent channel stuffing, among other things, violating federal securities laws. The case remains ongoing.
Then, on July 13, 2020, the Company disclosed it received subpoenas from the U.S. Attorney’s Office for the Northern District of Georgia and the U.S. Securities and Exchange Commission related to the above issues.
KSF’s investigation is focusing on whether Mohawk’s officers and/or directors breached their fiduciary duties to Mohawk’s shareholders or otherwise violated state or federal laws.
If you have information that would assist KSF in its investigation, or have been a long-term holder of Mohawk shares and would like to discuss your legal rights, you may, without obligation or cost to you, call toll-free at 1-877-515-1850 or email KSF Managing Partner Lewis Kahn ([email protected]), or visit https://www.ksfcounsel.com/cases/nyse-mhk/ to learn more.
About Kahn Swick & Foti, LLC
KSF, whose partners include former Louisiana Attorney General Charles C. Foti, Jr., is one of the nation’s premier boutique securities litigation law firms. KSF serves a variety of clients – including public institutional investors, hedge funds, money managers and retail investors – in seeking to recover investment losses due to corporate fraud and malfeasance by publicly traded companies. KSF has offices in New York, California and Louisiana.
To learn more about KSF, you may visit www.ksfcounsel.com.
Kahn Swick & Foti, LLC
Lewis Kahn, Managing Partner
1100 Poydras St., Suite 3200
New Orleans, LA 70163
SOURCE Kahn Swick & Foti, LLC
MegaFans and IGDA Foundation Partner for Charity eSports Tournaments Series
SAN DIEGO, Sept. 4, 2020 /PRNewswire/ — MegaFans (Mobile eSports Gaming Fanatics), a San Diego area-based mobile-casual eSports platform, has partnered with the International Game Developers Association Foundation again to produce a series of charity fundraising events using MegaFans eSports tournament platform and mobile-casual eSports games. The first tournament runs September 1 – 30, 2020 and is featured on the popular mobile eSports puzzle game, Candy Boo – Tournament Edition. The eSports tournaments are being promoted to raise awareness and funds to go toward the IGDA Foundation’s Diversity Initiative, to improve lives of game developers around the world.
The inaugural tournament in the series is being played on the popular, massive multi-player game, Candy Boo eSports Tournament Edition with over 100,000 downloads. Candy Boo Tournament Edition games are available on both the Apple and Google Play Stores and can be found at https://apps.apple.com/us/app/candy-boo-esports-tournament/id1447419350 and https://play.google.com/store/apps/details?id=com.megafans.candyboo&hl=en_US respectively. MegaFans is offering virtual and real prizes to the first 76 winners of the tournament. There is a live leader board inside the game that allows players to see their position.
The IGDA Foundation eSports Tournament is fun, challenging and easy to enter: Download the game, register with an email address or mobile phone number and make in-app purchases for tokens to play the game. Revenue from the token purchases go to the IGDA Foundation as donations and are tax deductible. Prizes will be matched with donations to the IGDA Foundation. Players and supporters are also encouraged to make direct donations outside the eSport tournament to the Camp Pendleton USO, by visiting https://igdafoundation.org.
Previously, MegaFans worked with the IGDA Foundation on the Stay in the Game Relief Fund which raised over $100,000 and MegaFans was the third-largest publicly active contributor.
About MEGAFANS Inc.
MegaFans Inc. is a mobile casual eSports gaming platform company that develops, publishes and manages turnkey, integrated software solutions for mobile games, enabling them to offer a competitive eSports tournament environment for the audience which increases retention, monetization and community growth through this novel approach. MegaFans delivers an inclusive, richer experience for the 2.5 billion mobile casual gaming community globally.
About IGDA Foundation
The IGDA Foundation advances a diverse workforce and ecosystem for the video game industry to better reflect the millions of passionate players enjoying video games worldwide.
The IGDA-F focuses on promoting a game development community representative of, and welcoming and inclusive to, every person who wants to make games. The IGDA-F garners support for diversity and inclusion in the video game industry with initiatives such as its IGDA Scholars, Velocity and Next Gen Leaders programs, with others in the pipeline.
The IGDA Foundation is a public charity, registered as a 501(c)(3) organization in the United States.
To find out more about the IGDA Foundation’s initiatives visit http://igdafoundation.org.
Erickson Inc. und Bell Textron Inc. geben unterzeichnete Verträge zum Beginn der Übertragung von Musterzulassungen für die Hubschrauber Bell 214st und B/B1 bekannt
PORTLAND, Oregon, 5. September 2020 /PRNewswire/ — Erickson Inc. und Bell Textron Inc. haben die Unterzeichnung von Verträgen bekannt gegeben, um die Übertragung der Musterzulassungen für die Hubschraubermodelle 214 ST und B/B1 an Erickson Incorporated einzuleiten. Die Übertragung wird durch die US-Luftfahrtbehörde FAA bearbeitet und der Abschluss wird für das Ende des Jahres erwartet.
Die Verträge ersetzen den vorigen Vertrag über Lizenz und Produktsupport, der von den Firmen 2015 unterzeichnet wurde. Erickson ist einer der größten Betreiber des 214ST und macht sich an den nächsten Schritt, die Leistungsverbesserung und betriebliche Nachhaltigkeit der 214-Plattform zu unterstützen, wie man es für die 1992 erworbene S-64-Plattform getan hat. Erickson wird mit Bell an der Übertragung der entscheidenden verbleibenden Funktionen und Verfahren arbeiten, um die volle Unterstützung der Musterzulassungen zu ermöglichen.
„Der 214 ist eine sehr gute Drehflügel-Gebrauchsplattform. Wir sind zuversichtlich, unseren innovativen Geist und unsere betriebliche Erfahrung dafür einzusetzen, für diesen Hubschrauber eine Zukunft zu gestalten, wie wir es in den letzten 30 Jahren bereits für den Helikopter S-64 Air Crane® getan haben. Die 214-Modelle sind eine willkommene Ergänzung des Portfolios unterstützter Luftfahrzeuge von Erickson.” – Doug Kitani, CEO
INFORMATIONEN ZU ERICKSON
Erickson ist ein führender globaler Anbieter von Luftfahrtdienstleistungen mit Fokus auf Verteidigung und nationale Sicherheit, Fertigung, Wartung/Reparatur/Überholung (MRO) und Dienstleistungen für den zivilen Markt. Zu den Herstellungs- und MRO-Diensten von Erickson gehört der Bau des Helikopters S-64 Aircrane® als Erstausrüster (OEM) und man ist ein wichtiger Zulieferer für zahlreiche OEMs der Luft- und Raumfahrt. Zu den kommerziellen Luftverkehrsdienstleistungen gehört der Betrieb von 20 S-64 Aircrane® Helikoptern in Besitz und Betrieb von Erickson, die für die Brandbekämpfung, den Bau von Hochspannungsleitungen, die Holzernte, Klimatechnik und spezialisierte Schwertransporte für die Branchen Öl und Gas eingesetzt werden. Erickson wurde 1971 gegründet und hat seinen Hauptsitz in Portland im US-Bundesstaat Oregon, mit Niederlassungen in Nordamerika, Südamerika, Europa, dem Nahen Osten, Afrika, dem Raum Asien-Pazifik und Australien.
INFORMATIONEN ZU BELL TEXTRON INC.
Wir denken weiter und weiter hinaus. Seit mehr als 80 Jahren denken wir die Erfahrung des Fliegens, und wo es uns hinführen kann, neu.
Wir sind Vorreiter. Wir waren die ersten, die die Schallmauer durchbrachen und einen kommerziellen Helikopter zur Zulassung brachten. Wir haben an der ersten Mission der NASA zum Mond teilgenommen und modernste Schwenkrotorsysteme auf den Markt gebracht. Heute definieren wir die Zukunft der On-demand-Mobilität.
Das Unternehmen ist eine hundertprozentige Tochtergesellschaft der Textron Inc. und hat seinen Sitz in Fort Worth (Texas) mit strategischen Niederlassungen weltweit. Fast ein Viertel unserer Belegschaft hat in der Armee gedient und wir engagieren uns dafür, unsere Streitkräfte zu unterstützen, ihre Aufgaben zu erfüllen.
Vor allem aber liefern unsere bahnbrechenden Innovationen unseren Kunden herausragende Erfahrungen. Effizient. Zuverlässig. Und stets mit der Sicherheit als Priorität.
WEITERE INFORMATIONEN ÜBER UNSERE PRODUKTE UND DIENSTE ERHALTEN SIE UNTER ERICKSONINC.COM
SOURCE Erickson Incorporated
WHO experts acclaim Arawana as an oil of the 5G era, and they recommend the consumption of trans-fat-free cooking oils
FIBRA Prologis Anuncia a Carlos Elizondo Mayer Serra como nuevo Miembro Independiente del Comité Técnico
FIBRA Prologis Appoints Carlos Elizondo Mayer-Serra as a New Independent Member of the Technical Committee
XTQZZZ on Vitality’s six-man roster: “We’re going to make substitutions mid-series depending on the map”
OG move past Evil Geniuses in BLAST Premier Fall Series
Boneyard Bunker Codes in Warzone: How to Open Both
Sunoco LP Maintains Quarterly Distribution
CVG Announces Third Quarter 2020 Conference Call
EA Modifies The Sims 4 Expansion pack and Trailer Out of Consideration for Korean Players
Warzone Punisher Pumpkin Bug: What’s the Issue?
FIFA 21 Global Series: Full List of FGS Swaps 1 Events
Taseko Reports $32 Million of Adjusted EBITDA in the Third Quarter 2020
Spencer: Xbox is Not Currently Planning Which Zenimax IP Will Be Exclusives
New England Whalers replace FURIA in IEM Beijing-Haidian
NAVI defeat NiP in BLAST Premier Fall Series opener
What the VR is Going on at Facebook? Accounts, Store Content and the Splits
Jay-Z announces new line of cannabis products dubbed Monogram
The Rockefeller Foundation commits USD1 billion to catalyze a green recovery from pandemic
PJM Named a Top Adoption-Friendly Company in the United States for 14th Consecutive Year
Top 10 Blockchain-as-a-Service (BaaS) Providers
Defining Value in Supplier Selection: An NSK Perspective
LBE VR: Past, Present and Post Civid Future
Do I need to Buy One Whole Bitcoin? 3 BTC Questions I’m Tired of Answering
olofmeister to step in for FaZe in BLAST Premier as NiKo nears move to G2 – Report
ReneSola Power and Novergy to Form Joint Venture to Develop Solar Projects in the UK
S&P Global Platts Announces Finalists for ‘Leadership in Energy Transition Award’
Founder´s Packs now available for the first AAA blockchain game BLANKOS BLOCK PARTY
Kevin Hart Jokingly Calls Crypto “Voodoo Money” While Kanye West Takes Bitcoin Seriously on Joe Rogan’s Podcast
Lenovo to Sell Varjo’s Enterprise VR Headsets
The Virtual Arena: The Ascendance of Arena-Scale Entertainment – Part 2
ICL Agrees to Acquire Fertiláqua, a Leading Brazilian Specialty Plant Nutrition Company
How these fintech partnerships are shaking up finance
Four key storylines of BLAST Premier Fall Series
FMC Corporation Announces New Executive Role, Vice President and Chief Sustainability Officer, and Elects New Vice President of Procurement and Global Facilities
Ant Group Chairman Eric Jing: Blockchain Will be the New Standard of the Future Financial Infrastructure
Cross border payments part 1: the competition is really, really old
Decarbonization Plus Acquisition Corporation Completes Initial Public Offering
SESCO Lighting Announces new CEO
Discussing roster changes, recent tournaments, and NA teams in Europe on HLTV Confirmed S5E12 with smooya
Techcrunch1 week ago
Original Content podcast: It’s hard to resist the silliness of ‘Emily in Paris’
Blockchain6 days ago
Bitcoinnami Officially Launches on October 21, 2020
Startups1 week ago
Solve the ‘dead equity’ problem with a longer founder vesting schedule
Startups1 week ago
Three views on the future of media startups
Startups1 week ago
Pear hosted its invite-only demo day online this year; here’s what you might have missed
Startups1 week ago
VCs reload ahead of the election as unicorns power ahead
Esports1 week ago
Legendary Pokémon encountered in Sword and Shield’s Dynamax Adventures have 100-percent catch rate
Techcrunch1 week ago
This Week in Apps: Apple’s big event, lidar comes to iPhone, Android gets a new IDE