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Tag: genome

Human Artificial Chromosomes Could Ferry Tons More DNA Cargo Into Cells

The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA...

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This Gene Increases the Risk of Alzheimer’s. Scientists Finally Know Why

At the turn of the 20th century, Dr. Alois Alzheimer noticed peculiar changes in a freshly removed brain. The brain had belonged to a...

Colossal Creates Elephant Stem Cells for the First Time in Quest to Revive the Woolly Mammoth

The last woolly mammoth roamed the vast arctic tundra 4,000 years ago. Their genes still live on in a majestic animal today—the Asian elephant.With...

Efficiently fine-tune the ESM-2 protein language model with Amazon SageMaker | Amazon Web Services

In this post, we demonstrate how to efficiently fine-tune a state-of-the-art protein language model (pLM) to predict protein subcellular localization using Amazon SageMaker. ...

Cellular Self-Destruction May Be Ancient. But Why? | Quanta Magazine

IntroductionIt can be hard to tell, at first, when a cell is on the verge of self-destruction. It appears to be going about its usual...

Genome India Project: Mapping India’s DNA

A remarkable achievement has been unlocked in the Genome India project as researchers have successfully decoded the genetic information of 10,000 healthy individuals from...

Gene Silencing Slashes Cholesterol in Mice—No Gene Edits Required

With just one shot, scientists have slashed cholesterol levels in mice. The treatment lasted for at least half their lives.The shot may sound like...

Functional analysis of single enzymes combining programmable molecular circuits with droplet-based microfluidics – Nature Nanotechnology

Greenough, L. et al. Adapting capillary gel electrophoresis as a sensitive, high-throughput method to accelerate characterization of nucleic acid metabolic enzymes. Nucleic Acids Res....

A Multitalented Scientist Seeks the Origins of Multicellularity | Quanta Magazine

IntroductionIn Cassandra Extavour’s office at Harvard University hangs a placard with a painted rainbow flag and a friendly invitation. “You are welcome here,” it reads. “I...

A ‘Lobby’ Where a Molecule Mob Tells Genes What to Do | Quanta Magazine

IntroductionThe discovery during the Human Genome Project in the early 2000s that we humans have only about 20,000 protein-coding genes — about as many...

How the quantum world can help scientists engineer biology

Feb 12, 2024 (Nanowerk News) CRISPR-Cas is a tool that allows scientists to make targeted changes to an organism’s DNA. This tool consists of two...

Partially Synthetic Moss Paves the Way for Plants With Designer Genomes

Synthetic biology is already rewriting life.In late 2023, scientists revealed yeast cells with half their genetic blueprint replaced by artificial DNA. It was a...

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