Interest in THC alternatives like Delta-8 and Delta-10 has been rapidly growing. Global Google searches for “Delta-8" alone went up over 700% from 2020 to 2021. Before, cannabis lovers needed…
Introduction “The internet is becoming the town square for the global village of tomorrow as humbly stated by Bill Gates”. The way we interact and [...]
Hemp has a million uses (including alternatives for building materials, plastics, paint, leathers, and more) many of which were important in history, and have been slowly coming back into use with the end of prohibition for hemp products. What is one of the newer hemp uses to start making it back to the public? ‘Hempanol’, […]
Universities have a vital role in preparing thousands for careers in the cannabis industry. There is an urgent need to train students to deal with legal, financial, marketing, product development, medical care, and technology issues relating to the cannabis industry. At the current growth rates, the cannabis industry will support over 400,000 jobs this year, so it is best to fill these positions with competent individuals who have been appropriately trained.
Chimeric antigen receptor (CAR) T cells have revolutionized cancer treatment. CARs use antibody-derived binding domains to redirect T cells to antigens expressed on the surface of cancer cells. However, the high affinity of most currently used CAR-binding domains results in excessive T-cell activation limiting CAR T-cell persistence and the inability to differentiate between antigen-high tumor cells and antigen-low healthy cells. We review recent data on the use of low-affinity CAR-binding domains and evaluate technologies and approaches to engineer and screen low-affinity antibody variants for CAR T-cell development.
Kratom is a tree in the coffee family, native to Southeast Asia with closely related species found in Africa. In those regions, medicinal and recreational use of kratom dates back centuries. As natural wellness has become a hot topic of discussion over the last decade, kratom is gaining popularity in the United States as well. It’s […]