As we enter a new decade in the digital age, data management has become a top priority for many high-value industries, especially pharmaceutical and healthcare companies. This sector strives to keep pace with the increased demand of COVID-19, as well as burgeoning technologies and the rapid globalization of supply chains.
Innovations in technology have provided pharmaceutical and healthcare companies with efficient data processing, real-time information and an unprecedented level of supply chain visibility. However, the ever-changing nature of their supply chains can leave companies vulnerable to theft and emerging cyber risks. With the proper technologies, companies in these high-risk sectors can add layers of protection against cyber-security threats, counterfeiting, cargo theft and temperature excursions, among other costly risks.
Overhaul and Freightwaves have come together to analyze the risks and solutions surrounding pharmaceutical logistics as part of a white paper report, Command and Control for Pharmaceutical Logistics.
Logistical issues such as temperature fluctuations and cargo theft have heightened the need for a unified command-and-control center that can overlay multiple data sources for one analytical tool. Companies that adopt this tool not only have access to a global view of their shipments but also possess a competitive marketplace advantage.
Pharmaceutical supply chains are becoming increasingly complex, and a growing number of exchange points have complicated the path from production to consumption. New modes of transport also make the likelihood of error even greater as bad weather and traffic congestion can result in additional delays.
Delays not only cost time and money, but also leave entire shipments vulnerable to temperature fluctuations. According to the IQVIA Institute for Human Data Science, the biopharma industry loses $35 billion annually due to failures in temperature-controlled logistics. Pharmaceutical Commerce estimates that by 2022, 30 of the top 50 global pharmaceutical products will require cold chain handling, as in-transit control over temperature, humidity, vibration and light become priorities.
Over-the-road (OTR) trucking is still one of the least secure forms of transportation globally, making the movement of high-value pharmaceuticals by truck a risky venture. It is estimated that the average pharmaceutical cargo theft is valued at $121,185. While in-transit cargo theft is a major concern, an extra set of padlocks is no match for invisible attacks in the form of malware and ransomware.
A 2018 Proofpoint report stated that among Fortune 500 companies, cyber attackers targeted the pharmaceutical industry the most. What often catches the attention of cyber-criminals is the rich intellectual property associated with prescription medicines.
Counterfeiting is also an ever-looming threat. In addition to the loss of sales and damaged reputations, companies find themselves allocating much of their funding towards combating fraudulent drugs, leaving less money available for groundbreaking research.
Moreover, counterfeiting can have deadly consequences. According to a 2017 report by PricewaterhouseCoopers (PwC), the counterfeit drug market is valued at $163 billion to $217 billion per year, making it the most lucrative sector of the global trade in illegally copied goods. The 2017 PwC report also revealed that 10% of all drugs in circulation are counterfeits. Beyond that, the American Society for Microbiology estimates that one million people die annually from ingesting fraudulent medications.
The white paper suggests that pharmaceutical and healthcare companies create security-enhanced audit trails that trace products throughout the supply chain. Evidence-based documentation can quickly mitigate potential risks and be very useful for healthcare companies, insurance companies, law enforcement and regulatory agencies should an investigation occur.
Regulations have been put in place to provide corrective action against supply chain threats. The whitepaper defines Good Distribution Practice (GDP) as the set of regulatory guidelines governing the wholesale distribution of medicinal products to ensure that their quality and integrity are maintained throughout the supply chain from manufacturer to end-user.
Pharmaceutical companies rely on guidelines such as GDP to mitigate risk. Failure to comply with these guidelines at any point within the supply chain can damage the product’s quality and cause an irreparable loss of public trust in the company. In addition, supply chain errors and irregularities can lead to Corrective Action, Preventative Action (CAPA), which is an important aspect of the GDP regulatory guidelines. A 2019 Pharma Manufacturing article reported that the financial cost for CAPA cases can range between $10 million and $1 billion, depending on the case’s severity.
Manufacturers invest significantly in quality-assurance monitoring, but their efforts are ultimately futile without a logistics monitoring system in place. The whitepaper states that the only way pharmaceutical companies can ensure the quality and safety of their products is through supply chain visibility at each step of the process.
Smart platforms like Overhaul have programmed artificial intelligence (AI) to take corrective action when a step in the supply chain does not meet standard operating procedures (SOPs). This AI technology could alert the party in control of the shipment or notify authorities when shipments have been tampered with or stolen. Its intelligent notification system works in real-time by connecting users to touchpoints in the supply chain and can alert law enforcement agencies when illegal in-transit activity is detected.
The use of real-time data streamlines communication between operations and drivers, while eliminating unnecessary paperwork. The whitepaper states that real-time data also protects the product’s integrity as high-value pharmaceuticals are transported through lower-security modes of transit like OTR. Notifications can be sent if truckload tampering is detected on stopped loads such as broken seals.
Real-time insight into inventory levels also provides accurate forecasting and managing through periods of peak demand. Companies have traditionally relied on historical data to model future demand and inventory management. According to the white paper, assuming that next year will be similar to last year is just as dangerous as shocks to the system like COVID-19 happening regularly.
With the proper technologies, pharmaceutical and healthcare companies can easily attain real-time information to unlock total supply chain visibility. The COVID-19 pandemic has challenged medical supply chains to become faster and more secure. No company can fully insulate itself from the ever-evolving threats that emerge from an ever-changing market, but smart companies will utilize the right tools to protect itself from threats old and new.
Why Some States Have Mandated Emissions Testing
If having to schedule an emissions test has ever struck you as an inconvenience, you’ve probably wondered why some states have mandated emissions testing. 33 out of the 50 states require some form of emissions testing for civilians’ vehicles. The frequency may vary, but the reasons for doing so remain roughly the same. There are a few ways your vehicle could fail an emissions test, which may result in expensive repairs or even a ticket—quite the incentives to prepare your vehicle to pass.
The Environmental Protection Agency and Federal Laws
The Clean Air Act was established in 1970, permitting the EPA to establish National Ambient Air Quality Standards (NAAQS). These standards encourage the protection of public health and the environment, and they specify the limit of pollutants allowed in the air. Pollutants such as carbon monoxide, lead, and sulfur dioxide is consistently measured to make sure they don’t breach the maximum levels laid out by the Clean Air Act. Though the Act is enforced at a federal level, state governments get to determine how those levels are monitored—one being through emissions testing.
How States Differ
Emissions testing requirements and frequency are up to each state government’s discretion. Some states have mandated emissions testing for the same reason other states impose restrictions on local vehicle manufacturers: pollutant level control. For states that use testing as a means of pollutant control, their approaches to it may differ. For example:
- Some states demand emissions testing statewide. These states, including Massachusetts, call for every vehicle to pass the emissions test as part of an out-of-pocket safety inspection.
- Many states have mandated emissions testing that’s only required every two years in densely populated areas.
- Certain states, such as Florida and Nebraska, don’t require any testing.
How Areas Differ
If you live in an area with a significant population, your chances of having to get an emissions test are higher (if testing is not a statewide demand). The more heavily trafficked and urbanized an area, the greater need to enforce emissions tests for pollutant control.
Source: Christina Duron is a freelance writer for multiple online publications where she can showcase her affinity for all things digital. She has focused her career around digital marketing and writes to explore topics that spark her interest.
Tesla Giga Texas raises its 1st pillar, shows immediate progress after shifting to 24/7 operations
Tesla Giga Texas’ 24/7 construction shifts have already showed immediate progress, with crews recently erecting the first concrete pillar on the site. The sight of Gigafactory Texas’ first column rising marks a special milestone for the buildout of the facility’s Phase 1 area, highlighting the project’s impressive construction speed.
Drone operator Jeff Roberts (@peterdog15) took photos of the first pillar at Giga Texas. He arrived on site just in time to see the huge pillar being delivered on site and witnessed it rising from the ground, much like the rest of Gigafactory Texas will be in the coming months. Roberts happened to also break the news that Tesla would be switching to three shifts for Giga Texas’ construction, effectively speeding up its schedule.
According to fellow drone operator Joe Tegtmeyer, the concrete column was located in the “Great Big Pit” area. Tegtmeyer speculated that more pillars will be installed “to support gantry cranes for the stamping machine dyes” in the massive Gigafactory. His video also includes all the visible changes to the construction site, including the ongoing work being done to a clearing across State Highway 130, which may be the location of Tesla’s ecological paradise.
Based on all the work going on at Giga Texas daily, Tesla doesn’t seem to be wasting any time. Simultaneous construction projects are happening in different areas of the 2,000-acre piece of land. And more work will be done in the outskirts of Giga Texas, too. Recently, the Austin City Council approved a resolution to develop East Austin, an area near Giga Texas.
“(This resolution) brings some much needed focus to a long-neglected part of East Austin that’s basically on the precipice of really experiencing considerable growth,” said Council Member Natasha Harper-Madison. “This is our opportunity to really get it right and get ahead of unfettered growth with more proactive action in this area.”
The resolution seems, at least in part, to be in anticipation to the economic growth and development Giga Texas might bring to the East Austin area. Prior to the resolution’s approval, panelists at the second Annual East Austin Growth Summit projected that Tesla Gigafactory Texas could create 15,000 new jobs.
“(Tesla has) a reputation of wanting their suppliers close to them, and they’re going to make that request for critical suppliers. So, I wouldn’t be shocked if we had 50-plus companies move here to support this facility. My hope is that those 50 come but that they also find another 50 that are already here,” said Ed Latson, the executive director of the Austin Regional Manufacturers Association.
Watch the most recent flyovers of Gigafactory Texas.
SpaceX Crew Dragon aces third autonomous space station docking
Update: A SpaceX Crew Dragon has successfully performed an autonomous rendezvous and docking with the International Space Station (ISS) for the third time in a row and the first time with four astronauts aboard.
Near-flawless space station arrival now behind it, Crew Dragon has effectively kicked off what could be the longest continuous spaceflight of a crewed US spacecraft in the history of American space exploration. Barring surprises, Crew Dragon capsule C207 (deemed “Resilience” by its first crew) and its expendable trunk section will spend roughly 180 days in orbit, crushing the previous US record of 84 days set by an Apollo Command and Service Module spacecraft in 1973.
Crew Dragon’s first successful operational space station arrival also marks the beginning of a small but significant new era for the ISS, enabling a crew of seven astronauts – up from six – to continuously live and work aboard the 20-year-old orbital outpost. Thanks to the station’s well-quantified needs for regular maintenance and operational expertise, that new seventh crew member will ultimately be able to dedicate almost every working moment to doing science in orbit.
Meanwhile, ISS NASA astronaut Kate Rubins hinted to SpaceX and NASA ground control that a range of photos she took of Crew Dragon’s third ISS arrival were likely to be spectacular. A ground controller took no time to respond with the quip that “[Crew Dragon] is known objectively to be a very good-looking vehicle.” Stay tuned for another update when those approach photos go live.
Approximately two hours after Crew Dragon’s third successful docking, Rubins successfully completed an array of tasks and opened the spacecraft’s hatch, allowing NASA astronauts Mike Hopkins, Shannon Walker, Victor Glover, and JAXA astronaut Soichi Noguchi to officially depart Dragon and join the International Space Station’s existing crew of three.
A SpaceX Crew Dragon is set to rendezvous and dock with the International Space Station for the third time later tonight and its four-astronaut crew took some time during their 27-hour flight to give live viewers a tour of the brand new spacecraft.
Emphasizing just how much space Crew Dragon offers its astronaut passengers once in orbit, the tour also included a minor tradition for NASA astronaut Victor Glover’s first orbital spaceflight. Astronauts Soichi Noguchi, Mike Hopkins, and Shannon Walker – all spaceflight veterans – commemorated Glover’s milestone with the gift of a small, golden pin, continuing a decades-old tradition.
If Crew Dragon remains in good health, the four astronauts will officially kick off the first ISS docking attempt with a 90-second thruster burn shortly after 9 pm EST (02:00 UTC).
Quite similar to Crew Dragon’s flawless Demo-2 astronaut launch debut, the Crew-1 spacecraft is scheduled to arrive at what is known as the ISS keep-out sphere around half an hour after its final major course-change thruster burn. Dragon will pause approximately 400m (~1300 ft) from the space station and wait for ground and station teams to give it the go-ahead to continue to another stopped point 20m (65 ft) out.
Altogether, the Crew-1 Dragon docking process will take about 55 minutes after the spacecraft enters the keep-out sphere and will culminate with a ‘soft’ capture around 11pm EST (04:00 UTC) and a ‘hard’ capture – signified by the docking port firmly bolting Dragon to the ISS – a bit less than 15 minutes later.
Orbital sunset is expected roughly 10 minutes before docking, meaning that Crew Dragon’s Crew-1 docking should be sunlit from a distance of ~1000 to 20 meters (3300 to 65 ft) from the ISS. Tune in below to watch the historic docking live.
Tesla (TSLA) to join S&P 500 December 21st
Tesla (NASDAQ: TSLA) is set to join the S&P 500 after being snubbed from the index in early September. The electric automaker will officially join the S&P 500 on Monday, December 21st, 2020.
The S&P announced:
“On November 16, 2020, S&P DJI announced that TSLA will be added to the S&P 500 effective prior to the open of trading on Monday, December 21 to coincide with the December quarterly rebalancing effective date.”
According to StreetInsider.com, the S&P Dow Jones Indices is seeking feedback through a consultation to determine which companies will be removed and whether TSLA will be added all at once. Because of TSLA’s massive valuation, which is the largest among carmakers in the world, it could be added to the S&P in two tranches.
The S&P also detailed this in a statement, according to CNBC.
“Due to the large size of the addition, S&P Dow Jones Indices is seeking feedback through a consultation to the investment community to determine if Tesla should be added all at once on the rebalance effective date or in two separate tranches ending on the rebalance effective date.”
After the news of TSLA’s inclusion in the index, its stock spiked over 10% in after-hours trading. After closing at $408.09 on Monday, the stock was trading at $450.47 as of 5:40 PM EST.
The addition of Tesla to the S&P will broaden the investor base, according to Bloomberg News. In order to join the index, companies must be based in the United States, and must be listed on the New York Stock Exchange, the NASDAQ, or the CBOE, and have a market capitalization of $8.2 billion or more. Additionally, a company must report four consecutive profitable quarters.
In 2020, Tesla has seen its stock price skyrocket based on advanced EV tech, battery improvements, and overall increases in demand and deliveries. Because of Tesla’s growth in the automotive market, the company has been focusing on building a new production facility in the United States and in Europe to fulfill consumer needs. Additionally, the company has marked five-straight profitable quarters and is coming off of its most successful three-month span as a company in terms of production and delivery figures.
Disclaimer: Joey Klender is a TSLA Shareholder.
Rinlo, Paper Beast & More Win Raindance Immersive Awards
upGrad Acquires TGA, Forays Into the INR 400 Billion Test Preparation Market in India
5 Reasons You May Not Want to Install macOS 11
Bitcoin IRA Accounts Are Soaring as Bitcoin Passes $18,000
Fauna Introduces New Capabilities to Help Development Teams Collaborate and Build More Secure and Responsive Business Applications
Orange Business Services Forms Global Strategic Collaboration Agreement with Amazon Web Services to Accelerate Customers’ Innovation in the Cloud
FDA Clears First of Its Kind Algorithm Suite for Personal ECG
The Free Asgard’s Wrath Offer Extended to all Oculus Quest 2 Owners
Trintech Client ABB Named Winner in 13th Annual Ventana Research Digital Leadership Awards
Redsun Services is Selected as a Constituent Stock of FTSE Global Micro Cap ex US Index
Microsoft Released an Out-of-Band Update for Windows to Address Authentication Issues
Sinopec kickstarts extensive research on CO2 emissions peak and carbon neutral
Adverty is granted US patent for in-game ad viewability technology BrainImpression™
Oslo, Los Angeles, Cidade do México e Budapeste estão empenhados na construção limpa para levar a indústria da construção a um futuro sustentável
Oslo, Los Angeles, Mexico et Budapest s’engagent à construire des bâtiments propres pour mener l’industrie du bâtiment vers un avenir durable
OMRON Strengthens Engagement with AliveCor with Series E Investment, Reinforces Cross-company Alliance for Remote Cardiovascular Condition Management
Evox Therapeutics expands its existing exosome patent portfolio
Husqvarna Group is further expanding its offering in surface preparation through the acquisition of Blastrac
Divestment by Sasol Chemicals North America LLC of its 50% Equity Interest in Gemini HDPE LLC
Trillium Gold Signs Agreement to Acquire 15,000 Hectares in the Confederation Greenstone Belt
Satellite imagery used for electricity consumption forecasting in Africa for the first time in new service
Vulnerabilities Allowed Hackers to Change Passwords of TikTok Accounts
Fujitsu and LARUS Leverage Power of Graph Database and Graph Explainable AI Technologies to Strengthen Detection of Credit Card Fraud
Four Seasons Total Landscaping and Ragstock team up for a Christmas…
Kredivo Closes up to US$100m Warehouse Financing Facility with Victory…
New York startup Mai launched with two social media unicorns in Asia…
South Metro Housing Options joins the Rocky Mountain E-Purchasing…
Online 529 Education Gifting Programs Fulfill Families’ Ecommerce…
New PlayStation VR Mega Pack Includes 5 Games and Camera Adaptor
Ven VR Adventure Confirmed for Oculus Quest, Rift Launch in December,
Energy1 day ago
ADAMA Mourns Death of Joe Krkoska, Executive Vice President of Global Operations
Blockchain4 days ago
Ethereum on a Tear as It Breaks New Yearly High
Nano Technology1 week ago
CCNY & partners in quantum algorithm breakthrough
Blockchain5 days ago
Ethereum 2.0 Sees $10 Million Stake from Dubai-Based Investment Firm
Blockchain5 days ago
Bitcoin Begins to Stall After Parabolic Ascent
Nano Technology1 week ago
Anions matter: Zinc-ion hybrid capacitors with ideal anions in the electrolyte show extra-long performance
Blockchain5 days ago
Deutsche Bank Says Investors Increasingly Prefer Bitcoin Over Gold as Inflation Hedge
Nano Technology1 week ago
Arrowhead Interim Clinical Data Demonstrate ARO-AAT Treatment Improved Multiple Biomarkers of Alpha-1 Liver Disease