The role of microalgae in the bioeconomy.
New Biotechnol. 2021; 61: 99-107
Producing omega-3 polyunsaturated fatty acids: a review of sustainable sources and future trends for the EPA and DHA market.
Resources. 2020; 9: 148
Marine bioactives: from energy to nutrition.
Trends Biotechnol. 2021; ()
Valuable products from biotechnology of microalgae.
Appl. Microbiol. Biotechnol. 2004; 65: 635-648
Benefits of using algae as natural sources of functional ingredients.
J. Sci. Food Agric. 2013; 93: 703-709
Omega-3 fatty acid production from enzyme saccharified hemp hydrolysate using a novel marine thraustochytrid strain.
Bioresour. Technol. 2015; 184: 373-378
Algal biotechnology for pursuing omega-3 fatty acid (bioactive) production.
Microbiol. Aust. 2017; 38: 85-88
Carotenoid synthesis: Retrospect and recent progress.
Arch. Biochem. Biophys. 2009; 483: 224-228
Carotenoid composition of three bloom-forming algae species.
Food Res. Int. 2014; 65: 215-223
Blooms like it hot.
Science. 2008; 320: 57-58
Microalgae as sources of high added-value compounds – a brief review of recent work.
Biotechnol. Prog. 2011; 27: 597-613
Microalgae as a new source of bioactive compounds in food supplements.
Curr. Opin. Food Sci. 2016; 7: 73-77
Microalgae as source of functional ingredients in new-generation foods: challenges, technological effects, biological activity, and regulatory issues.
Crit. Rev. Food Sci. Nutr. 2021; ()
The nutritional and pharmacological potential of new Australian thraustochytrids isolated from mangrove sediments.
Mar. Drugs. 2020; 18: 151
Thraustochytrids as production organisms for docosahexaenoic acid (DHA), squalene, and carotenoids.
Appl. Microbiol. Biotechnol. 2016; 100: 4309-4321
Taxonomy, ecology and biotechnological applications of thraustochytrids: A review.
Biotechnol. Adv. 2018; 36: 26-46
Omega-3 microbial oils from marine thraustochytrids as a sustainable and technological solution: A review and patent landscape.
Trends Food Sci. Technol. 2020; 99: 244-256
The lipid metabolism in thraustochytrids.
Prog. Lipid Res. 2019; 76101007
Are Thraustochytrids algae?.
Fungal Biol. 2017; 121: 835-840
Compositional shift in lipid fractions during lipid accumulation and turnover in Schizochytrium sp.
Bioresour. Technol. 2014; 157: 107-113
Omega-3 biotechnology: Thraustochytrids as a novel source of omega-3 oils.
Biotechnol. Adv. 2012; 30: 1733-1745
Heterotrophic culturing of microalgae.
in: Slocombe S.P. Benemann J.R. Microalgal Production for Biomass and High-Value Products. CRC Press, 2016: 15
Propyl gallate and butylated hydroxytoluene influence the accumulation of saturated fatty acids, omega-3 fatty acid and carotenoids in thraustochytrids.
J. Funct. Foods. 2015; 15: 186-192
Analysis of the biosynthetic process of fatty acids in Thraustochytrium.
Biochimie. 2018; 144: 108-114
Proposal of a new thraustochytrid genus Hondaea gen. nov. and comparison of its lipid dynamics with the closely related pseudo-cryptic genus Aurantiochytrium.
Algal Res. 2018; 35: 125-141
Biosynthetic mechanism of very long chain polyunsaturated fatty acids in Thraustochytrium sp. 26185 [S].
J. Lipid Res. 2016; 57: 1854-1864
Mechanisms of fatty acid synthesis in marine fungus-like protists.
Appl. Microbiol. Biotechnol. 2015; 99: 8363-8375
Very long chain polyunsaturated fatty acids accumulated in triacylglycerol are channeled from phosphatidylcholine in Thraustochytrium.
Front. Microbiol. 2019; 10: 645
Thraustochytrid cell factories for producing lipid compounds.
Trends Biotechnol. 2021; 39: 648-650
Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production.
Microb. Cell Factories. 2012; 11: 96
Systems approach to quantify the global omega-3 fatty acid cycle.
Nat. Food. 2020; 1: 59-62
A survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2011.
Molecules. 2013; 18: 3641-3673
Lipids accumulation in Rhodotorula glutinis and Cryptococcus curvatus growing on distillery wastewater as culture medium.
Environ. Prog. Sustain. Energy. 2013; 32: 69-74
Nutraceuticals and functional foods: Whole versus processed foods.
Trends Food Sci. Technol. 2009; 20: 376-387
Docosahexaenoic acid from algal oil.
Eur. J. Lipid Sci. Technol. 2013; 115: 965-976
Microbial and genetically engineered oils as replacements for fish oil in aquaculture feeds.
Biotechnol. Lett. 2017; 39: 1599-1609
Pollen baiting facilitates the isolation of marine thraustochytrids with potential in omega-3 and biodiesel production.
J. Ind. Microbiol. Biotechnol. 2013; 40: 1231-1240
High cell density cultivation of a novel Aurantiochytrium sp. strain TC 20 in a fed-batch system using glycerol to produce feedstock for biodiesel and omega-3 oils.
Appl. Microbiol. Biotechnol. 2013; 97: 6907-6918
Exploring omega-3 fatty acids, enzymes and biodiesel producing thraustochytrids from Australian and Indian marine biodiversity.
Biotechnol. J. 2016; 11: 345-355
Study of cellular development and intracellular lipid bodies accumulation in the thraustochytrid Aurantiochytrium sp. KRS101.
Bioresour. Technol. 2014; 161: 149-154
Biodiesel production from heterotrophic oleaginous microalga Thraustochytrium sp. BM2 with enhanced lipid accumulation using crude glycerol as alternative carbon source.
Bioresour. Technol. 2020; 306123113
Life cycle assessment: heterotrophic cultivation of thraustochytrids for biodiesel production.
J. Appl. Phycol. 2015; 27: 639-647
Suitability of novel algal biomass as fish feed: accumulation and distribution of omega-3 long-chain polyunsaturated fatty acid in zebrafish.
Appl. Biochem. Biotechnol. 2019; 188: 112-123
Screening of new British thraustochytrids isolates for docosahexaenoic acid (DHA) production.
J. Appl. Phycol. 2017; 29: 2831-2843
Evaluation of fish meal and fish oil replacement by soybean protein and algal meal from Schizochytrium limacinum in diets for giant grouper Epinephelus lanceolatus.
Aquaculture. 2016; 452: 1-8
Extracted microbial oil from a novel Schizochytrium sp. (T18) as a sustainable high DHA source for Atlantic salmon feed: Impacts on growth and tissue lipids.
Aquaculture. 2021; 534736249
May omega-3 fatty acid dietary supplementation help reduce severe complications in Covid-19 patients?.
Biochimie. 2020; 179: 275-280
Marine protists and rhodotorula yeast as bio-convertors of marine waste into nutrient-rich deposits for mangrove ecosystems.
Protist. 2020; 171125738
Squalene: potential chemopreventive agent.
Expert Opin. Investig. Drugs. 2000; 9: 1841-1848
TLC screening of thraustochytrid strains for squalene production.
J. Appl. Phycol. 2014; 26: 29-41
Novel squalene-producing thraustochytrids found in mangrove water.
Biosci. Biotechnol. Biochem. 2017; 81: 2034-2037
Energy innovation potential of oleaginous microalgae.
Biofuels. 2012; 3: 761-781
Comparison of thraustochytrids Aurantiochytrium sp., Schizochytrium sp., Thraustochytrium sp., and Ulkenia sp. for production of biodiesel, long-chain omega-3 oils, and exopolysaccharide.
Mar. Biotechnol. 2014; 16: 396-411
Thraustochytrid marine protists: production of PUFAs and other emerging technologies.
Mar. Biotechnol. (NY). 2008; 10: 631-640
Bead milling for lipid recovery from thraustochytrid cells and selective hydrolysis of Schizochytrium DT3 oil using lipase.
Bioresour. Technol. 2016; 200: 464-469
Enzymatic activities of epiphytic and benthic thraustochytrids involved in organic matter degradation.
Aquat. Microb. Ecol. 2005; 41: 299-305
Alkaline lipase activity from the marine protists, thraustochytrids.
World J. Microbiol. Biotechnol. 2011; 27: 2125-2131
Integrating metagenetics and high-throughput screening for bioprospecting marine thraustochytrids producers of long-chain polyunsaturated fatty acids.
Bioresour. Technol. 2021; 125176
Integration of lipidomic and transcriptomic profiles reveals novel genes and regulatory mechanisms of Schizochytrium sp. in response to salt stress.
Bioresour. Technol. 2019; 294122231
Lipid distribution pattern and transcriptomic insights revealed the potential mechanism of docosahexaenoic acid traffics in Schizochytrium sp. A-2.
J. Agric. Food Chem. 2019; 67: 9683-9693
Biotechnological production of lipid and terpenoid from thraustochytrids.
Biotechnol. Adv. 2021; 48107725
Mathur, A.S. et al. Indian Oil Corp. Ltd., Department of Biotechnology. Thraustochytrid based process for treating waste effluents, US9890402B2
The strategies to reduce cost and improve productivity in DHA production by Aurantiochytrium sp.: from biochemical to genetic respects.
Appl. Microbiol. Biotechnol. 2020; 104: 9433-9447
Novel biorefinery approach aimed at vegetarians reduces the dependency on marine fish stocks for obtaining squalene and docosahexaenoic acid.
ACS Sustain. Chem. Eng. 2020; 8: 8803-8813
Characterization and comparison of lipid and PUFA production by native thraustochytrid strains using complex carbon sources.
Heliyon. 2020; 6e05404
Integrated consolidated bioprocessing for simultaneous production of omega-3 fatty acids and bioethanol.
Biomass Bioenergy. 2020; 137105555
Mining of squalene as a value-added byproduct from DHA producing marine thraustochytrid cultivated on food waste hydrolysate.
Sci. Total Environ. 2020; 736139691
A biorefinery approach to obtain docosahexaenoic acid and docosapentaenoic acid n-6 from Schizochytrium using high performance countercurrent chromatography.
Algal Res. 2021; 55102241
Combining engineering strategies and fermentation technology to enhance docosahexaenoic acid (DHA) production from an indigenous Thraustochytrium sp. BM2 strain.
Biochem. Eng. J. 2018; 133: 179-185
Combined metabolome and lipidome analyses for in-depth characterization of lipid accumulation in the DHA producing Aurantiochytrium sp. T66.
Metabolites. 2021; 11: 135
Engineering xylose metabolism in thraustochytrid T18.
Biotechnol. Biofuels. 2018; 11: 248
Dynamic flux balance analysis of biomass and lipid production by Antarctic thraustochytrid Oblongichytrium sp. RT2316-13.
Biotechnol. Bioeng. 2020; 117: 3006-3017
A new strategy for strain improvement of Aurantiochytrium sp. based on heavy-ions mutagenesis and synergistic effects of cold stress and inhibitors of enoyl-ACP reductase.
Enzym. Microb. Technol. 2016; 93-94: 182-190
Improvement of fatty acid productivity of thraustochytrid, Aurantiochytrium sp. by genome editing.
J. Biosci. Bioeng. 2021; 131: 373-380
Genetic tool development in marine protists: emerging model organisms for experimental cell biology.
Nat. Methods. 2020; 17: 481-494
Comparison of cell disruption methods for improving lipid extraction from thraustochytrid strains.
Mar. Drugs. 2015; 13: 5111-5127
Supercritical CO2 extraction of Aurantiochytrium sp. biomass for the enhanced recovery of omega-3 fatty acids and phenolic compounds.
J. CO2 Util. 2020; 38: 24-31
Optimization of enzymatic cell disruption for improving lipid extraction from Schizochytrium sp. through response surface methodology.
J. Oleo Sci. 2018; 67: 215-224
Extraction of bio-oils from algae with supercritical carbon dioxide and co-solvents.
J. Supercrit. Fluids. 2018; 135: 60-68
Deep eutectic solvents as efficient solvents in biocatalysis.
Trends Biotechnol. 2019; 37: 943-959
A novel process for isolation and purification of polyunsaturated fatty acids from a thraustochytrid.
Algal Res. 2020; 46101806
Health effects of dietary phospholipids.
Lipids Health Dis. 2012; 11: 3
Dietary phospholipids: Role in cognitive processes across the lifespan.
Neurosci. Biobehav. Rev. 2020; 111: 183-193
Biodiesel from microalgae.
in: Gonzalez-Fernandez C. Muñoz R. Microalgae-Based Biofuels and Bioproducts. Woodhead Publishing, 2017: 235-258
Co-production of DHA and squalene by thraustochytrid from forest biomass.
Sci. Rep. 2020; 10: 1992
Detection of the oil-producing microalga Botryococcus braunii in natural freshwater environments by targeting the hydrocarbon biosynthesis gene SSL-3.
Sci. Rep. 2019; 9: 16974
Accumulation of lipid production in Chlorella minutissima by triacylglycerol biosynthesis-related genes cloned from Saccharomyces cerevisiae and Yarrowia lipolytica.
J. Microbiol. 2012; 50: 526-534
Overexpression of acetyl-CoA synthetase increased the biomass and fatty acid proportion in microalga Schizochytrium.
Appl. Microbiol. Biotechnol. 2013; 97: 1933-1939
Metabolic engineering to enhance biosynthesis of both docosahexaenoic acid and odd-chain fatty acids in Schizochytrium sp. S31.
Biotechnol. Biofuels. 2019; 12: 141
Integration of continuous-high cell density-fed-batch fermentation for Aurantiochytrium limacinum for simultaneous high biomass, lipids and docosahexaenoic acid production.
Bioresour. Technol. 2021; 325124636
Bioconversion of waste acid oil to docosahexaenoic acid by integration of ‘ex novo’ and ‘de novo’ fermentation in Aurantiochytrium limacinum.
Bioresour. Technol. 2021; 332125062
Development of a multi-stage continuous fermentation strategy for docosahexaenoic acid production by Schizochytrium sp.
Bioresour. Technol. 2018; 269: 32-39
Improved production of docosahexaenoic acid in batch fermentation by newly-isolated strains of Schizochytrium sp. and Thraustochytriidae sp. through bioprocess optimization.
Synth. Syst. Biotechnol. 2018; 3: 121-129
Improved docosahexaenoic acid production in Aurantiochytrium by glucose limited pH-auxostat fed-batch cultivation.
Bioresour. Technol. 2015; 196: 592-599
Impact of carbon and nitrogen feeding strategy on high production of biomass and docosahexaenoic acid (DHA) by Schizochytrium sp. LU310.
Bioresour. Technol. 2015; 184: 139-147
The relationship of oxygen uptake rate and kLa with rheological properties in high cell density cultivation of docosahexaenoic acid by Schizochytrium sp. S31.
Bioresour. Technol. 2014; 152: 234-240
Fatty acid shifts and metabolic activity changes of Schizochytrium sp. S31 cultured on glycerol.
Bioresour. Technol. 2013; 142: 255-260
Improvement of docosahexaenoic acid production on glycerol by Schizochytrium sp. S31 with constantly high oxygen transfer coefficient.
Bioresour. Technol. 2013; 142: 400-406
Food applications.
in: Galanakis C.M. Microalgae. Academic Press, 2021: 207-238
Sustainable production of food grade omega-3 oil using aquatic protists: Reliability and future horizons.
New Biotechnol. 2021; 62: 32-39
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