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Medical Marijuana for Myasthenia Gravis

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The neuromuscular disorder, Myasthenia Gravis, causes weakness in the skeletal muscles the body uses for movement. It happens because the communication between the nerve cells and muscles becomes impaired. The disruption in communication stops muscle contraction and the end result is the total muscle weakness. Myasthenia Gravis is one of the most common primary disorders of a neuromuscular disorder.

The name is derived from Latin and Greek that literally means ´grave muscle weakness´. The name is often harsher than what really occurs. With help, it is possible to live a normal life. The most common features of this condition are drooping eyelids, difficulty chewing and swallowing, and respiratory difficulties in severe cases.  

What is Myasthenia Gravis?

Myasthenia Gravis (MG) is an autoimmune disease that focusses on muscle weakness. The condition develops because of an insufficient amount of acetylcholine receptors on the postsynaptic membrane. Both acquired and congenital forms of MG can be found in cats, dogs, and humans. Myasthenia Gravis is a disorder of the space between your nerves and muscles also known as the neuromuscular junction. The nerve responds to an electrical signal and releases neurotransmitters crossing this area to activate muscle contractions to move.

As an autoimmune disorder, MG causes the immune system to attack itself. As a result, the acetylcholine neurotransmitter receptors are reduced in function and number. The muscles do not receive sufficient signals to move and become weaker. The body´s immune system makes antibodies, called acetylcholinesterase, that block or destroys the receptors sites for the neurotransmitter acetylcholine.

Typical Symptoms of Myasthenia Gravis

MG can affect any skeletal muscle but those muscles most affected are those controlling movement of the eyelid and eye movement. Swallowing and facial expression movement are also more affected. It could affect muscles on the arms, legs, or chest too, but this does not happen frequently. The condition could appear suddenly, and the symptoms are often overlooked.

The symptoms that doctors often notice first, is the weakness of the eye muscles. Sometimes the first symptoms include also slurred speech and difficulty swallowing. Each individual demonstrates its own unique degree of the disorder. Sometimes it only affects ocular myasthenia where only the eye is affected. Other times it is more generalized, and more muscles are affected, including those that let you breathe. There is a variety of symptoms. They are:

Drooping eyelids

Blurred vision

Abnormal facial expressions

Difficulty swallowing

Impaired speech

Shortness of breath

Weak neck, limbs, and extremities

Some factors can influence or trigger the symptoms of myasthenia gravis. This includes the following:

Emotional stress

Surgery

Bright sunlight

Viral infections

Immunization

Menstruation

Medication like ciprofloxacin, chloroquine, lithium, procainamide, procaine, beta-blockers, and statins

How do you know you have Myasthenia Gravis?

A physical and neurological test will be performed by the doctor to see if a person suffers from Myasthenia Gravis? In a specific test, the following will be checked:

Checking for muscle weakness

Testing reflexes

Checking muscles tone

Studying muscle coordination

Examining eye movement

Testing body sensations

Checking motor functions like touching the finger to the nose

Performing repetitive nerve stimulation tests

Blood test for antibodies related to MG

Testing lung function

What are the treatments and can Cannabis help?

In the beginning, there was no treatment for myasthenia gravis, but fortunately, there are now some ways to deal with the disorder. Today, medication or surgery can help to deal with the disorder. The most common drug used to treat the condition is anticholinesterase medication. It works by slowing down the acetylcholine break down in the neuromuscular junction. But there are a number of side-effects with any of the traditional medicines. That is where cannabis comes in handy.

Cannabis as a medical aid has been used for many years. Long before modern medicine was practiced, cannabis was used to treat many physical and psychological complaints. The active ingredients of cannabis can help to decrease the symptoms of stress and anxiety. It can also help to regulate activity in the nervous system. Both THC and CBD have beneficial properties that influence the endocannabinoid system to produce various effects on the body and mind.

Medical marijuana acts very much like anticholinesterase agents. It inhibits the enzyme acetylcholinesterase responsible for acetylcholine degradation. By doing this there is more time for acetylcholine to interact with its receptors before breakdown. Cannabis helps to overcome the blocked receptor that causes muscle contractions.

CANNABIS FOR BELL’S PALSY, READ MORE..

CANNABIS FOR BELL'S PALSY

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TREMORS AND CANNABIS

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Source: http://cannabis.net/blog/medical/medical-marijuana-for-myasthenia-gravis

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Jay-Z announces new line of cannabis products dubbed Monogram

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Rapper and entrepreneur Jay-Z is launching his own cannabis brand in partnership with Caliva, the California-based weed company that hired the star as its chief brand strategist last year. 

Named Monogram, Jay-Z’s line of marijuana products launched its website and social media accounts on Friday.

“Monogram marks a new chapter in cannabis defined by dignity, care and consistency. It is a collective effort to bring you the best, and a humble pursuit to discover what the best truly means,” Monogram’s website highlights.

No further information on the specific products that will be sold under the Monogram brand has been released yet. 

However, according to the website, the flower used in Monogram’s products is grown in small batches, with a board of “cannabis experts” tasked with grading and hand-selecting each flower that goes into the line. 

The New York rapper joined Caliva in 2019 as a brand strategist, which entailed overseeing the creative direction of the company. Furthermore, Jay was focused on Caliva’s social equity efforts as he aimed to increase economic participation of people disproportionately harmed by marijuana prohibition in the newly legal industry. 

As for when consumers can expect to try Jay-Z new products, a spokesperson told the New York Daily News Monogram still hasn’t set its dispensary release schedule. The line will “definitely be available across all of California,” according to the spokesperson.

In other news, basketball star Shawn Kemp who played for the Seattle SuperSonics is also showing his love of pot. Kemp is set to open Seattle’s first black-owned marijuana dispensary this Friday. The Sonics legend named his dispensary Shawn Kemp’s Cannabis and is hoping to serve as a model for others in the black community who might be interested in foraying into the legal marijuana business in the area. 

“I’m looking forward to welcoming Sonics fans on a regular basis, starting with opening day. I hope that Shawn Kemp’s Cannabis will be an inspiration for people to get involved with the legal cannabis industry, especially people of color,” the Reign Man said in a press release. 

Source: https://greencamp.com/jay-z-announces-new-line-of-cannabis-products-dubbed-monogram/

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Analysis: Legal weed in Texas would generate over $500 million in tax revenue per year

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Legalizing marijuana in Texas could generate over half a billion dollars in tax revenue per year and create more than 40,000 new jobs, according to the results of a report released by Vicente Sederberg LLP earlier this month. 

Legal cannabis sales in Texas would reach about $2.7 billion annually based on the fact that there are more than 1.5 million residents over the age of 21 that consume pot on a monthly basis, the analysis calculated. 

The estimated tax revenue was calculated under the assumption Texas would tax marijuana sales at the same rate as Colorado at 20.6%. This would amount to $1.1 billion in taxes per biennium, while Texas could collect an additional $10 million per year through the issuing of marijuana business licenses.

The report notes Colorado has raised nearly $13 million on average per year just from license and application fees. Furthermore, the report indicated that current taxpayer dollars that go towards marijuana arrests and prosecutions amount to $311 million per year – money that Texas would save should it legalize pot.  

“States across the country are seeing the benefits of legalizing and regulating cannabis. It is inspiring lawmakers in prohibition states to reexamine the efficacy and costs of their current policies and take a closer look at the alternatives,” said Shawn Hauser, a partner at Vicente Sederberg.

“The goal of this report is to provide a snapshot of the economic benefits Texas would experience if it started treating cannabis more like alcohol for adults 21 years of age and older,” he commented on the new report

Aside from the tax revenue that legal weed in Texas could generate, the report highlighted marijuana’s job creation potential. An estimated 20,000 to 40,000 new jobs would be available in the newly legal industry, with tens of thousands of additional indirect positions, the report estimated.  

Hauser also pointed out the added economic benefits of legalization in Texas given current uncertainties provoked by the coronavirus pandemic.

“Texas is leaving an enormous amount of money on the table by keeping cannabis illegal,” according to him. 

Texas was once known for having the strictest drug laws in the U.S., but the state has softened its stance on cannabis in recent years. A very limited medical marijuana program was established in 2015, while, more recently, cannabis possession arrests in the state have been significantly declining after hemp became legal.   

Source: https://greencamp.com/analysis-legal-weed-in-texas-would-generate-over-500-million-in-tax-revenue-per-year/

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Cannabis Businesses Invest in Their Futures with Political Donations

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Cannabis companies have been making political donations for years, and in 2020, those donations have continued to grow. In fact, some companies are investing aggressively to shape the future of the cannabis industry either by donating directly to campaigns and politicians or through political action committees (PACs) that support cannabis-friendly candidates and legislation.

So far in 2020, the Center for Responsive Politics reports that the leading cannabis companies, cannabis-related companies, and cannabis trade associations making donations to federal candidates, parties, and outside groups are (in order of 2020 donation amounts to date):

  1. Canty Ventures
  2. National Cannabis Industry Association (NCIA)
  3. Have A Heart
  4. Beyond Broadway LLC
  5. Sea Hunter Therapeutics
  6. Cannabis Trade Federation
  7. MedMen
  8. Dan Kopp & Co
  9. Acreage Holdings
  10. Weedmaps
  11. Trulieve

Compare that list to the list of large cannabis company donors in 2019, which included Curaleaf, Parallel Brands (formerly Surterra Wellness), Tweed Inc. (part of Canopy Growth Corporation), Canndescent, and Trulieve. Even ancillary cannabis companies like Dama Financial, WeedMaps, and Acreage Holdings donate large sums of money in 2019 according to data from the Center for Responsive Politics.

State Donations in 2020

There are a number of legalization (adult-use and/or medical use) and decriminalization measures on state ballots in 2020, and cannabis companies, ancillary companies, and professional associations have been actively donating directly to related campaigns and initiatives at the state level.

In Arizona, Harvest is the biggest donor in support of legalization (Prop. 207) followed by Curaleaf, MedMen, Cresco Labs, Copperstate Farms, Arizona Dispensaries Association, Herbal Wellness Center, and Oasis Dispensaries.

Mississippi’s medical marijuana initiative on the November ballot (Initiative 65) has received donations from the CEO of Heritage Properties (George Walker III), Ghost Management Group (which owns Weedmaps), and the owner of ABKO Labs (Robert Lloyde II).

Ghost Management Group and its Weedmaps subsidiary also donated to support Montana’s and New Jersey’s legalization initiatives. In addition, New Jersey’s legalization Question 1 on the November ballot received donations directly from The Scotts Company (the maker of Scotts Miracle Gro), Pashman Stein Walder Hayden (a New Jersey cannabis law firm), and Compassionate Care Research Institute (a New Jersey dispensary).

Keep in mind, these donations don’t include the donations that cannabis companies and ancillary businesses donate to PACs or that they invest in lobbying. The Center for Responsive Politics reports that the biggest investments in lobbying from cannabis companies, ancillary companies, and trade associations in 2020 have come from the Cannabis Trade Federation, National Cannabis Roundtable, Canopy Growth Corp, Curaleaf, Global Alliance for Cannabis Commerce, Parallel Brands, Cronos Group, Charlotte’s Web, NCIA, Acreage Holdings, Dama Financial, Trulieve, California Cannabis Association, and Oregon Cannabis Association.

Political Donations from Cannabis Interests Are Not New

One of the biggest political donation stories happened in California when cannabis businesses donated aggressively to former Lieutenant Governor Gavin Newsom’s campaign to become the state’s governor in the 2018 election. According to the Los Angeles Times, he secured hundreds of thousands of dollars in donations from cannabis cultivators, processors, and retailers.

By May 2018, Newsom had raised nearly $500,000 from cannabis companies, but he wasn’t the only politician in California to receive money from cannabis interests. At the time, the state’s Treasurer, John Chiang, and Attorney General, Xavier Becerra, also secured donations from the cannabis industry

And of course, these donation numbers don’t even include the many donations from PACs that businesses and individuals working in the cannabis industry donate to. Many of these funds go directly to specific candidate’s fundraising efforts. For example, the Coastal Pacific Political Action Committee held a fundraiser in June 2017, and six days later, the PAC donated $50,000 to Newsom’s campaign.

Another noteworthy political donation happened in Florida over the course of multiple years. The Miami Herald reported that Surterra donated $1.1 million to Florida political candidates and committees between the summer of 2016 and March 2018. Trulieve donated $564,000 during the same period, and Curaleaf donated $469,000.

In Illinois, the doors for cannabis companies to make political donations opened in March 2017 when a federal judge ruled an Illinois provision that did not allow marijuana companies to make campaign contributions in the state was unconstitutional.

According to the Chicago Tribune, the provision prevented contributions to political committees that were established for the purpose of promoting candidates for public office. Since that decision was made, cannabis companies like PharmaCann and Cresco Labs have donated significant amounts to the state’s political candidates and committees.

Business and individual donations to marijuana-friendly political candidates have also become standard in Nevada and Colorado. During the 2016 elections, dozens of marijuana cultivators, processors, and dispensaries donated $75,000 to Nevada legislators according to the Nevada Independent.

Looking back further in history, Florida Senator Rob Bradley received his first donation from a cannabis company in 2015 when Costa Farms donated $10,000 to his political committee.

Similarly, cannabis businesses have actively contributed to Colorado political campaigns for years, and many of those businesses have been holding political fundraisers to support their preferred candidates. PBS reported back in 2014 that Colorado’s congressional delegation had received $20,000 during the first nine months of 2014 from marijuana businesses. Also in 2014, a fundraiser to support political candidates that was held by Tripp Keber of Denver, Colorado’s Dixie Elixirs & Edibles generated $40,000 in donations.

What’s Next for Political Campaign Donations from Cannabis Businesses?

As the cannabis industry continues to grow and more states legalize medical and/or recreational cannabis, laws will continue to evolve. Cannabis businesses and ancillary businesses should absolutely be concerned about which politicians are making those laws.

With that said, it’s safe to assume that political donations from the cannabis industry will get larger and more frequent in the coming years. Let’s put the donations from cannabis companies to political campaigns into perspective. During the first half of 2019, the cannabis industry gave more than $200,000 to members of Congress, which was up from $248,504 donated throughout all of 2018. Compare that to the $42 million that pharmaceutical companies donated to political campaigns across the United States in 2018.

With those numbers in mind, it’s guaranteed that political donations from cannabis and cannabis-related companies will continue to grow. Savvy businesses are paying attention and getting involved in an attempt to influence the regulations that could make or break their companies’ futures.

Originally published 8/24/17. Updated 10/23/20.

Source: https://cannabiz.media/marijuana-businesses-invest-in-their-futures-with-political-donations/

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