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Biotechnology

Link Reservations Inc/LinkResPet (LRSV) To Start Selling CBD Products on Amazon US

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London, UK, June 8, 2021 – Link Reservations Inc. (OTC Pink: LRSV) (the “Company”), a provider of medicinal mushroom and cannabidiol (CBD) wellness products for both humans and pets, announces it intends to start selling its LinkResPet and DailyLifeCBD products on Amazon.com. The Company would stock its LinkResPet cat and dog CBD products, as well as its DailyLifeCBD mushroom-infused Immune product, on the online platform.

Rene Lauritsen, Link Reservations Inc CEO commented: “This is something we are very excited about as it will open up our retail avenues to include more sources of revenue. Amazon has become ever-present in our society, and a great first point of purchase for anyone looking for CBD, hemp or mushroom products. By selling on Amazon, we would be able to reach a larger audience looking for wellness solutions and so increase our revenue. Our intention is to initially stock our products on Amazon US but we hope to also operate on the UK based platform (amazon.co.uk) at a later date.”

LinkResPet’s products consist of CBD tinctures for dogs and cats. While DailyLifeCBD has a functional mushroom and CBD range of products including its DailyLifeCBD Immune tincture, as well as other CBD products in the pipeline. All products are made with the highest quality hemp oil and are lab tested, THC and GMO free. The hemp oil used in LRSV products comes from organically grown certified U.S. and European hemp. The Company ensures that its products undergo a rigorous process of quality control and testing using the latest scientific methods.

For more information about LinkResPet or to purchase CBD products for pets, please visit www.linkrespet.com or follow us on Twitter: @res_pet.

For more information about DailyLifeCBD, the Company’s range of CBD and mushroom product for people, please visit to learn more or purchase: https://dailylifecbd.com/.

About Link Reservations Inc.
Link Reservations Inc is a CBD and wellness product provider dedicated to improving the health and life conditions of both people and pets worldwide. Its trades through its two brands; LinkResPet and DailyLifeCBD. LinkResPet develops and markets hemp-based CBD products for cats, dogs and horses. DailyLifeCBD provides everyday hemp based CBD wellness and mushroom products for people. The Company has operations in both the US and Europe.

Forward-Looking Statements & Disclaimers:
The information in this Press Release includes certain “forward-looking” statements within the meaning of the Safe Harbor provisions of Federal Securities Laws, as that term is defined in section 27a of the United States Securities Act of 1933, as amended, and section 21e of the United States Securities Exchange Act of 1934, as amended. Statements in this document, which are not purely historical, are forward-looking statements and include any statements regarding beliefs, plans, expectations or intentions regarding the future. Investors are cautioned that such statements are based upon assumptions that in the future may prove not to have been accurate and are subject to significant risks and uncertainties, including the future financial performance of the Company. Although the Company believes that the expectations reflected in its forward-looking statements are reasonable, it can give no assurance that such expectations or any of its forward-looking statements will prove to be correct. Readers are cautioned not to place undue reliance on these forward-looking statements that speak only as of the date of this release, and the Company undertakes no obligation to update publicly any forward-looking statements to reflect new information, events, or circumstances after the date of this release except as required by law.

Link Reservations Inc.
400 Thames Valley Park Drive
Reading Berkshire RG6 1 PT
United Kingdom
Phone: +44 330 808 0897

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Source: https://otcprwire.com/link-reservations-inc-linkrespet-lrsv-to-start-selling-cbd-products-on-amazon-us/

Biotechnology

Explainer: How Synthetic Biology is Redesigning Life

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In the modern digital world, social media reach is power.

The people with the most followers on Twitter, for example, have a massive platform to spread their messages, while those with large, engaged followings on Instagram are an advertiser’s dream sponsor partner.

Social media can also be an equalizer of power. It’s true that many celebrities boast large followings across platforms, but social media has also enabled previously unknown personalities to turn YouTube or TikTok fame into veritable star power and influence.

Who has the biggest reach across the entire social media universe? Instead of looking at who has the most followers on Instagram, Twitter, or other networks, we ranked the most-followed personalities across all major platforms combined.

Who Has the Most Overall Followers on Social Media?

We parsed through hundreds of the most-followed accounts on multiple platforms to narrow down the top influencers across social media as of April 2021.

Sources include trackers of the most followers on Twitter, Instagram, Facebook, YouTube, Twitch, and TikTok, verified directly on site and with social media tracker Socialblade.

The results? A top 50 list of social media influencers consisting of athletes, musicians, politicians, and other personalities.

Rank Name Category Total Followers Biggest Platform
#1 Cristiano Ronaldo Sports 517M Instagram
#2 Justin Bieber Music 455M Instagram
#3 Ariana Grande Music 429M Instagram
#4 Selena Gomez Music 425M Instagram
#5 Taylor Swift Music 361M Instagram
#6 Dwayne Johnson Film & TV 342M Instagram
#7 Katy Perry Music 338M Instagram
#8 Kylie Jenner Other 333M Instagram
#9 Rihanna Music 332M Twitter
#10 Kim Kardashian Other 319M Instagram
#11 Lionel Messi Sports 298M Instagram
#12 Neymar Sports 283M Instagram
#13 Shakira Music 282M Facebook
#14 Jennifer Lopez Music 277M Instagram
#15 Beyoncé Music 267M Instagram
#16 Ellen DeGeneres Film & TV 260M Instagram
#17 Miley Cyrus Music 235M Instagram
#18 Nicki Minaj Music 232M Instagram
#19 Barack Obama Politics 221M Twitter
#20 Will Smith Film & TV 217M Facebook
#21 Kendall Jenner Other 212M Instagram
#22 Demi Lovato Music 211M Instagram
#23 Lady Gaga Music 210M Twitter
#24 Kevin Hart Film & TV 201M Instagram
#25 Virat Kohli Sports 195M Instagram
#26 Eminem Music 194M Facebook
#27 Drake Music 192M Instagram
#28 Khloé Kardashian Other 191M Instagram
#29 Bruno Mars Music 191M Facebook
#30 Chris Brown Music 187M Instagram
#31 Vin Diesel Film & TV 177M Facebook
#32 Narendra Modi Politics 175M Twitter
#33 Justin Timberlake Music 175M Twitter
#34 Billie Eilish Music 171M Instagram
#35 Charli D’Amelio Other 169M TikTok
#36 Kourtney Kardashian Other 165M Instagram
#37 Cardi B Music 160M Instagram
#38 LeBron James Sports 157M Instagram
#39 Adele Music 156M Facebook
#40 Priyanka Chopra Film & TV 144M Instagram
#41 Germán Garmendia Gaming 143M Youtube
#42 Wiz Khalifa Music 142M Facebook
#43 Felix “PewDiePie” Kjellberg Gaming 141M Youtube
#44 Akshay Kumar Film & TV 140M Instagram
#45 Snoop Dogg Music 138M Instagram
#46 Deepika Padukone Film & TV 138M Instagram
#47 Britney Spears Music 137M Twitter
#48 Shawn Mendes Music 136M Instagram
#49 Whindersson Nunes Batista Other 135M Instagram
#50 Salman Khan Film & TV 134M Facebook

Unsurprisingly, celebrities reign supreme on social media. As of April 2021, soccer superstar Cristiano Ronaldo was the most-followed person on social media with more than 500 million total followers.

But there are other illuminating highlights, such as the global reach of music. With large and diverse fanbases, artists account for half of the top 50 largest social media followings.

Also notable is the power of Instagram, which was the biggest platform for 67% of the top 50 social media influencers. This includes hard-to-categorize celebrities like the Kardashians and Jenners, which turned reality TV and social media fame into business and media empires.

Download the Generational Power Report (.pdf)

The Generational Power Index

The Most Followers on Twitter, TikTok, and YouTube

However, it’s not only celebrities that dominate social media.

Personalities that started on one social media platform and developed massive followings include TikTok’s most-followed star Charli D’Amelio and YouTubers Germán Garmendia, Felix “PewDiePie” Kjellberg, and Whindersson Nunes Batista.

Politicians were also prominent influencers. Former U.S. President Barack Obama has the most followers on Twitter, and India’s Prime Minister Narendra Modi has more than 175 million followers across social media.

Former U.S. President Donald Trump would have also made the list with more than 140 million followers across social media before being banned from multiple platforms on January 8, 2021.

A Generational Look at Social Media Influence

While older generations have had to adapt to social media platforms, younger generations have grown up alongside them. As a measure of cultural importance, this gives Gen X, Millennials, and Gen Z a rare leg-up on older generations.

Millennials, in particular, hold the lion’s share of spots in this top 50 list:

Generation # of Influencers in Generation Top Influencer in Generation
Gen Z 4 Kylie Jenner
Millennial 33 Cristiano Ronaldo
Gen X 10 Dwayne (The Rock) Johnson
Baby Boomer 3 Ellen DeGeneres

The average age of the top 50 influencers was just over 37.

In our Generational Power Index (GPI), which measures the share of power generations hold in various categories, digital platforms were a key area where Millennials derived their power and influence. Overall, Baby Boomers—and to a lesser extent, Gen X—still run the show in most areas of society today.

Social Media Influence, Going Forward

As most fans and advertisers know, not all social media accounts and followings are homogenous.

Many influencers with relatively small followings have more consistent engagement, and are often able to demand high advertising fees as a result.

Conversely, most social media platforms are reckoning with a severe glut of fake accounts or bots that inflate follower counts, impacting everything from celebrities and politicians to personalities and businesses.

Regardless, social media has become a mainstay platform (or soapbox) for today’s cultural influencers. Billions of people turn to social media for news, engagement, recommendations, and entertainment, and new platforms are always on the rise.

Editor’s Note: An earlier version of the data used for this story incorrectly counted Facebook likes instead of followers for some personalities. The content has since been corrected and updated.”

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Source: https://www.visualcapitalist.com/how-synthetic-biology-redesigns-life/

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Bioengineer

Mechanical engineer receives NSF CAREER award to pioneer robot-assisted rehabilitation

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Project outcomes have potential to transform treatment of walking disabilities across wide range of conditions

Zach Lerner, an assistant professor in Northern Arizona University’s Department of Mechanical Engineering, was recently awarded a $538,563 grant from the National Science Foundation (NSF) to build on his research into restoring neuromuscular function and augmenting human ability through the design, control and testing of robotic exoskeletons.

“There is a critical need for treatments that address the root causes of walking disability, including impaired strength, muscle control and coordination. This project seeks to advance the scientific study of walking rehabilitation and pioneer a novel wearable rehabilitation strategy,” Lerner said. “The outcomes of this project have the potential to transform the treatment of walking disabilities across a wide range of conditions.”

Grant is NSF’s most prestigious award in support of junior faculty

The award was made to Lerner by the NSF through its Faculty Early Career Development (CAREER) Program, a foundation-wide activity that offers the NSF’s most prestigious awards “in support of early-career faculty who have the potential to serve as academic role models in research and education and to lead advances in the mission of their department or organization. Activities pursued by early-career faculty should build a firm foundation for a lifetime of leadership in integrating education and research.”

The funding will support Lerner’s goal to optimize long-term gait rehabilitation through hybrid ankle exoskeleton training, working with a team that includes both graduate and undergraduate students in his Biomechatronics Lab on NAU’s Flagstaff campus.

While wearable robotic exoskeletons hold potential for individuals with walking disabilities, prior research has focused on immediate improvements in walking performance from powered assistance. This project seeks to understand whether alternating assistance and resistance with a wearable ankle exoskeleton will elicit greater improvements in walking than either approach alone.

“This funding will support us in establishing fundamental knowledge on the interplay between disease severity and wearable assistance and resistance,” Lerner said. “The strategies we develop will be generalizable, enabling other investigators to apply this framework to different types of control algorithms, devices, joints and patient populations.”

Project to integrate research and education

The five-year project will also enable Lerner and his team to offer opportunities for educational and outreach activities to engage elementary and middle school students as well as college students. Lerner will develop a new Curriculum in Assistive Robotics and Engineering (CARE), incorporating advanced robotics course modules, design-for-disability capstone projects and K-12 experiences.

“Through this new curriculum,” Lerner said, “we aim to motivate engineering students to address the challenges experienced by individuals with disabilities and improve engineering education on human-centered design. We anticipate that the students involved in CARE will gain an improved understanding of the needs of people with physical disabilities, which will translate into effective engineering solutions, and result in more motivated, insightful and impactful engineering students and professionals.”

###

About Northern Arizona University

Northern Arizona University is a higher-research institution providing exceptional educational opportunities in Arizona and beyond. NAU delivers a student-centered experience to its nearly 30,000 students in Flagstaff, statewide and online through rigorous academic programs in a supportive, inclusive and diverse environment. Dedicated, world-renowned faculty help ensure students achieve academic excellence, experience personal growth, have meaningful research opportunities and are positioned for personal and professional success.

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Source: https://bioengineer.org/mechanical-engineer-receives-nsf-career-award-to-pioneer-robot-assisted-rehabilitation/

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Biotechnology

School of Engineering second quarter 2021 awards

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Members of the MIT engineering faculty receive many awards in recognition of their scholarship, service, and overall excellence. The School of Engineering periodically recognizes their achievements by highlighting the honors, prizes, and medals won by faculty working in our academic departments, labs, and centers.

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Source: https://news.mit.edu/2021/school-engineering-second-quarter-awards-0621

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AI

Each of These Microscopic Glass Beads Stores an Image Encoded on a Strand of DNA

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Increasingly, civilization’s information is stored digitally, and that storage is abundant and growing. We don’t bother deleting those seven high-definition videos of the ceiling or 20 blurry photos of a table corner taken by our kid. There’s plenty of room on a smartphone or in the cloud, and we count on both increasing every year.

As we fluidly copy information from device to device, this situation seems durable. But that’s not necessarily true.

The amount of data we create is increasing rapidly. And if we (apocalyptically) lost the ability to produce digital storage devices—hard drives or magnetic tape, for example—our civilization’s collective digital record would begin to sprout holes within years. In decades, it’d become all but unreadable. Digital storage isn’t like books or stone tablets. It has a shorter expiration date. And, although we take storage for granted, it’s still expensive and energy hungry.

Which is why researchers are looking for new ways to archive information. And DNA, life’s very own “hard drive,” may be one solution. DNA offers incredibly dense data storage, and under the right conditions, it can keep information intact for millennia.

In recent years, scientists have advanced DNA data storage. They’ve shown how we can encode individual books, photographs, and even GIFs in DNA and then retrieve them. But there hasn’t been a scalable way to organize and retrieve large collections of DNA files. Until now, that is.

In a new Nature Materials paper, a team from MIT and Harvard’s Broad Institute describe a DNA-based storage system that allows them to search for and pull individual files—in this case images encoded in DNA. It’s a bit like thumbing through your file cabinet, reading the paper tabs to identify a folder, and then pulling the deed to your car from it. Only, obviously, the details are bit more complicated.

“We need new solutions for storing these massive amounts of data that the world is accumulating, especially the archival data,” said Mark Bathe, an MIT professor of biological engineering and senior author of the paper. “DNA is a thousandfold denser than even flash memory, and another property that’s interesting is that once you make the DNA polymer, it doesn’t consume any energy. You can write the DNA and then store it forever.”

How to Organize a DNA Storage System

How does one encode an image in a strand of DNA, anyway? It’s a fairly simple matter of translation.

Each pixel of a digital image is encoded in bits. These bits are represented by 1s and 0s. To convert it into DNA, scientists assign each of these bits to the DNA’s four base molecules, or nucleotides, adenine, cytosine, guanine, and thymine—usually referred to in shorthand by the letters A, C, G, and T. The DNA bases A and G, for example, could represent 1, and C and T could represent 0.

Next, researchers string together (or synthesize) a chain of DNA bases representing each and every bit of information in the original file. To retrieve the image, researchers reverse the process, reading the sequence of DNA bases (or sequencing it) and translating the data back into bits.

The standard retrieval process has a few drawbacks, however.

Researchers use a technique called a polymerase chain reaction (PCR) to pull files. Each strand of DNA includes an identifying sequence that matches a short sequence of nucleotides called a PCR primer. When the primer is added to the DNA solution, it bonds with matching DNA strands—the ones we want to read—and only those sequences are amplified (that is, copied for sequencing). The problem? Primers can interact with off-target sequences. Worse, the process uses enzymes that chew up all the DNA.

“You’re kind of burning the haystack to find the needle, because all the other DNA is not getting amplified and you’re basically throwing it away,” said Bathe.

MIT DNA data storage image microscopic glass beads
The microscopic glass spheres pictured here are DNA “files.” Each contains an image, encoded in DNA, and is coated in DNA tags describing the image within. Image Credit: Courtesy of the researchers (via MIT News)

To get around this, the Broad Institute team encapsulated the DNA strands in microscopic (6-micron) glass beads. They affixed short, single-stranded DNA labels to the surface of each bead. Like file names, the labels describe the bead’s contents. A tiger image might be labeled “orange,” “cat,” “wild.” A house cat might be labeled “orange,” “cat,” “domestic.” With just four labels per bead, you could uniquely label 1020 DNA files.

The team can retrieve specific files by adding complementary nucleotide sequences, or primers, corresponding to an individual file’s label. The primers contain fluorescent molecules, and when they link up with a complementary strand—that is, the searched-for label—they form a double helix and glow. Machines separate out the glowing beads, which are opened and the DNA inside sequenced. The rest of the DNA files remain untouched, left in peace to guard their information.

The best part of the method is its scalability. You could, in theory, have a huge DNA library stored in a test tube—Bathe notes a coffee mug of DNA could store all the world’s data—but without an easy way to search and retrieve the exact file you’re looking for, it’s worthless. With this method, everything can be retrieved.

George Church, a Harvard professor of genetics and well-known figure in the field of synthetic biology, called it a “giant leap” for the field.

“The rapid progress in writing, copying, reading, and low-energy archival data storage in DNA form has left poorly explored opportunities for precise retrieval of data files from huge…databases,” he said. “The new study spectacularly addresses this using a completely independent outer layer of DNA and leveraging different properties of DNA (hybridization rather than sequencing), and moreover, using existing instruments and chemistries.”

This Isn’t Coming For Your Computer

To be clear, all DNA data storage, including the work outlined in this study, remains firmly in the research phase. Don’t expect DNA hard drives for your laptop anytime soon.

Synthesizing DNA is still extremely expensive. It’d cost something like $1 trillion dollars to write a petabyte of data in DNA. To match magnetic tape, a common method of archival data storage, Bathe estimates synthesis costs would have to fall six orders of magnitude. Also, this isn’t the speediest technique (to put it mildly).

The cost of DNA synthesis will fall—the technology is being advanced in other areas as well—and with more work, the speed will improve. But the latter may be beside the point. That is, if we’re mainly concerned with backing up essential data for the long term with minimal energy requirements and no need to regularly access it, then speed is less important than fidelity, data density, and durability.

DNA already stores the living world’s information, now, it seems, it can do the same for all things digital too.

Image Credit: Courtesy of the researchers (via MIT News).

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Source: https://singularityhub.com/2021/06/20/each-of-these-microscopic-glass-beads-stores-an-image-encoded-on-a-strand-of-dna/

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