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CBD and Heart Arrhythmia: What We Know So Far

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The relationship between CBD and arrhythmia is somewhat complicated.

Contemporary scientific research shows that CBD has a potentially beneficial effect on arrhythmia, and on the cardiovascular system as a whole.

On the other hand, a small percentage of people experience an increased heart rate and heart palpitations when they use CBD, which are known symptoms of arrhythmia. 

Before we get into more details of the research, let’s briefly explain arrhythmia.

Cardiac arrhythmia is a group of conditions characterized by an irregular heartbeat, where the heart either beats too rapidly or too slowly. 

One of the main symptoms of arrhythmia are heart palpitations, which are characterized by increased awareness of the contraction of the heart, often accompanied by the hard and irregular beating of the heart.

Unlike CBD, which is non-psychoactive, THC (the most abundant psychoactive cannabinoid in the cannabis plant) is known to cause rapid heartbeat and heart palpitations.

This especially happens to novice users, but also if the user consumes too much THC at once.

This occurs because THC significantly lowers blood pressure, which causes the heart to pick up the pace and beat faster.

For a very large percentage of users, CBD doesn’t produce this effect but some people do experience irregular heartbeats and heart palpitations from consuming cannabidiol.

A good example of how rarely this happens is this 2019 study, which analyzed the effects of CBD on people suffering from chronic pain. 

This research had 97 patients (30 to 65 years old), and only one of them experienced an increased heartbeat from using CBD. 

Patients were using two soft gels per day for 8 weeks, and each soft gel contained 15.7mg of CBD, and 0.5mg of THC.

The woman who experienced a rapid heartbeat reported that the treatment “made her heart race”.

The reasons behind this occurrence are still unknown, but if it happens to you, it’s important to understand the difference between CBD products. 

Full-spectrum CBD products have a significant amount of THC, and other minor cannabinoids and terpenes are also present in these products.

If you’re especially sensitive to THC, these types of products can definitely induce a rapid heartbeat and palpitations.

Compared to full-spectrum products, broad-spectrum CBD products have a lesser amount of THC in them, and they also contain minor cannabinoids and terpenes. 

Broad-spectrum products are far less likely to induce palpitations, although it’s still possible. 

Finally, CBD isolates are the third type of CBD products. They only contain CBD, and nothing else. These products are least likely to cause a racing heart or palpitations.

It’s important to mention that CBD isolates are considered the least beneficial type of CBD products because cannabinoids work synergically in the body.

This synergistic cooperation of different cannabinoids is known as the entourage effect, because the presence of THC and other cannabinoids increases the health benefits of CBD.

Even though some users experience arrhythmia-like symptoms from CBD, an animal study from 2010 found that an acute administration of CBD suppressed ischaemia-induced arrhythmia. 

Ischaemia is a restriction of blood to tissues, which causes a shortage of oxygen that is necessary for keeping tissues alive. 

The researchers also stated that CBD reduced the size of infarction (tissue death), when it was given at reperfusion injury. 

A 2013 review mentioned that current evidence suggests CBD has positive effects on the cardiovascular system, but that clinical research on human participants is required to determine if these positive effects will translate to the human cardiovascular system.

Finally, a 2018 review stated that cannabinoids appear as promising therapeutic agents for cardiovascular diseases. 

Conclusion

Since the research on the effects of CBD on arrhythmia (and the cardiovascular system in general) is still in its starting phases, it probably isn’t wise to consume it for these purposes until more is known on the subject.

On the other hand, if you’re experiencing heart palpitations from CBD products, make sure to follow our guidelines regarding different types of CBD products.

If these heart-related symptoms persist, you can also consider lowering the dose or perhaps even discontinuing your CBD regimen.

Source: https://greencamp.com/cbd-and-heart-arrhythmia/

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Cannabis and the 2020 Election

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Next month, five states will be voting on seven ballot measures to legalize cannabis. A variety of proposals, including constitutional amendments, statutory initiatives, and alternative measures, could establish new medical cannabis markets in two states and expand legalization to include adult use legalization in four states. Three of these proposals would enshrine cannabis possession and consumption within state constitutions.

This article will explore the proposals themselves as well as the short-term implications of legalization on existing license holders and the industry.

2020 cannabis ballot measures policy focus

State-by-State Review

Arizona

Arizona voters have another opportunity to legalize cannabis next month, after narrowly defeating adult use legislation four years ago. In recent years, the Copper State’s medical cannabis market has seen significant MSO expansion, and new mandatory testing requirements launch at the beginning of November.

There are roughly 150 medical cannabis licenses in the state currently — all of which would receive priority status in the application process for adult use licensing. Additionally, diversity applicants and applicants in areas currently lacking cannabis retail access would be fast-tracked applicants.

Prop. 207 does include local control and opt-out provisions, and a new 16% tax would direct revenue to a variety of funds, while retail operators would be able to launch delivery services as soon as 2023.

Mississippi

Mississippi could become the 34th state to legalize cannabis for medical use, but two competing measures are creating complications on the ballot. A citizen-driven campaign led to the placement of Initiative 65, while the legislature responded with Alternative Initiative 65A.

Initiative 65 establishes a medical cannabis program similar to the program structure of many other states; with clearly defined qualifying conditions, possession limits, taxes, registration fees, and a regulator — the state health department. The alternative includes no definitions and only allows smokable cannabis products for terminally ill patients, leaving a highly restrictive market requiring enabling legislation.

Previous bills have been proposed, but never brought to a vote — leaving some skeptical that anything at all may come of Initiative 65A.

Montana

Montana’s existing medical cannabis program relies on a system of caregivers who cultivate cannabis and make manufactured products, including edibles and concentrates. Additionally, there is a limited number of licensed dispensaries throughout the state. Legalization would be a major evolution for Montana, which has seen multiple ballot initiatives and legislative interventions in recent years.

Two measures have been placed: one constitutional amendment to set the age of 21 as the minimum buying age and a measure to establish a commercial adult use market. While no early sales provisions are included, Montana companies would be the only businesses able to start sales for the first year after legalization.

New Jersey

New Jersey voters may make history, legalizing the adult use of cannabis and triggering a race among Mid-Atlantic states to implement sales first. While all of New Jersey’s neighbors have existing medical cannabis programs, none have taken steps to expand further. In recent years, numerous regional state legislatures have attempted to legalize, and Public Question 1 may tip the scales for an entire region with over 50 million residents.

The text of the amendment is brief, but it establishes a definition for ‘cannabis’ while permitting possession, use, and industry operations for adults ages 21 and up. The existing Cannabis Regulatory Commission would be tasked with regulating the industry, but the state legislature must first come to an agreement and pass enabling legislation.

Currently, New Jersey’s medical market includes roughly fifteen licenses, including cultivation and manufacturing, as well as a limited number of dispensaries. The next phase for cannabis in NJ is uncharted territory for now: it is unclear if existing licenses will be given the first opportunity to serve the general public.

Given licensing delays and a slow rollout in Illinois, lawsuits and delays could be in New Jersey’s future — with some analysts suggesting a four-year timeline from amendment passage to full implementation. This may be good news for MSOs, including Columbia Care, Verano, and Acreage Holdings, among others.

South Dakota

South Dakota has long been unfriendly to cannabis in all forms and has some of the nation’s strictest marijuana possession penalties. While other non-medical states have at least given a nod to low-THC medical hemp programs, the Mount Rushmore state hadn’t established any kind of hemp or cannabis program at all until the legislature passed industrial hemp legalization this past spring.

Now, the state could make history as the first to legalize cannabis for medical and adult use purposes at the same time. Two proposals are on the ballot: an initiated measure to launch a medical cannabis program, and a constitutional amendment to fully legalize cannabis, with provisions including adult use, a medical program, and expanded hemp legalization.

Medical use is enshrined in both proposals, while the constitutional amendment would prevent the legislature from any type of statutory tampering to limit a retail market. The constitutional amendment would establish a commercial market for both adult use and medical purposes. Medical use would include home cultivation. As there is no cannabis market in the state at this time, no businesses would be able to take advantage of “early sales” provisions, as seen in other states.

Analysis

Previously, medical cannabis programs and commercial licensing schemes predated adult use legalization, and the majority of these proposals came into existence by way of the ballot. In most of the earliest states to fully legalize, this was the case: Colorado, Washington, Alaska, Oregon, California, Massachusetts, and Nevada all had some form of voter-approved medical cannabis legislation first.

Implementation of adult-use legalization has, however, varied across the states. In these proposals, Arizona, Montana, and New Jersey have existing medical cannabis infrastructures, but the implementation of adult use will likely lead to program changes.

Some legalization measures have allowed for existing medical dispensaries to launch sales to adults during a period of late-stage rulemaking. These businesses have operated under modified compliance rules, with track-and-trace requirements and varying tax rates until legalization rules are completed.

After Oregon voters approved legalization in 2014, the state’s medical market rapidly expanded with early sales on the horizon. At one point, there were more medical dispensaries in the state than Starbucks or McDonald’s locations. That number later dropped as businesses converted their licenses over.

For some of the states with legalization on the ballot this year, the transition out of medical will pose challenges: product shortages, long customer lines, new tax rates, uncertainty over product offerings, and testing requirements on top of an already difficult pandemic business environment.

Overall, legalization measures promise to bring a significant impact to consumers and patients in Arizona, Mississippi, Montana, New Jersey, and South Dakota. It’s hard to quantify the short-term improvements to consumers and industry operators, as passage of these initiatives will set off a flurry of legislative and regulatory discussion over the holidays and into the spring. Existing licensees and hopeful applicants should keep an eye for new opportunities: public comment periods, application deadlines, and new sales opportunities on the horizon.

Source: https://cannabiz.media/cannabis-and-the-2020-election/

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Cuomo advisor predicts New York will legalize pot in April

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New York Governor Andrew Cuomo’s advisor on marijuana policy said this week the Empire State could legalize weed in April of next year with a bill that would serve as a model for other states looking to allow recreational pot in the United States.

Axel Bernabe, assistant counselor to Governor Cuomo, was a guest on the Under The Canopy series, recently launched by Canopy Growth, where he discussed cannabis legalization efforts in New York. According to Bernabe, a bill to legalize marijuana will be introduced through the state budget in January again, while he expects legalization to take effect by April. 

As New Jersey appears ready to legalize marijuana this November, Bernabe said the Cuomo administration has been watching its neighbor “closely.”

“We’re watching New Jersey closely. We’ve always been confident that we’d get to this before New Jersey, so if they pass the referendum they still have to have an agreement between the governor and the Senate over there,” he said.

“If New Jersey can beat us to it, they’ll get a gold star but I still think we’re gonna set the model for this,” Bernabe added, referring to the bill’s social equity provisions, among other things. 

During the interview, Bernabe also said that New York has been monitoring how legalization has been unfolding in Vermont, Maine, and Massachusetts, but has also consulted with states on the West Coast, where the legal pot industry is larger and more developed. 

Regarding hemp, Cuomo’s advisor said the state will release its guidelines and regulations for CBD consumer products early next year as well.

“Those products are already out there, so there’s no sense in pretending they’re not,” Bernabe explained. 

For this reason, the governor and his team have been working on guidelines, which will include maximum dose per serving labeling and warnings about potential THC content in various hemp-derived products. New York has copied a lot of Florida’s hemp regulations while crafting its own policies, Bernabe stated, before telling Canopy Growth’s David Culver that the administration is currently putting the finishing touches to the guidelines. 

Although Governor Cuomo promised his state would legalize weed soon, marijuana legalization was left out of the New York state budget for 2020 due to the coronavirus pandemic, which hit the state particularly badly earlier this year.

Cuomo previously proposed working in conjunction with the neighboring states of New Jersey, Connecticut, and Pennsylvania on coordinating a recreational marijuana system for the region. 

Source: https://greencamp.com/cuomo-advisor-predicts-new-york-will-legalize-pot-in-april/

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PURA Concludes Farmersville Meetings – Deal Imminent

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Dallas, TX – October 20, 2020 – OTC PR WIRE — Puration, Inc. (OTC PINK: PURA) today announced that CEO Brian Shibley concluded a key meeting yesterday essential to finalizing the acquisition of 72-acre property in Farmersville, Texas central to the company’s recently announced Farmersville Brands strategy.  “The acquisition is imminent. Look for an announcement very soon,” said Mr. Shibley.

PURA has scheduled the release of a comprehensive update this Friday, October 23, 2020, to provide the latest information on progress with the Farmersville Brand strategy. The Friday update this Friday will include the latest on the company’s planned dividend of PAO Group, Inc. (OTC PINK: PAOG) stock in conjunction with PURA’s sale of its cannabis cultivation business to PAOG.

For more information on Puration, visit http://www.purationinc.com

Disclaimer/Safe Harbor:

This news release contains forward-looking statements within the meaning of the Securities Litigation Reform Act. The statements reflect the Company’s current views with respect to future events that involve risks and uncertainties. Among others, these risks include the expectation that any of the companies mentioned herein will achieve significant sales, the failure to meet schedule or performance requirements of the companies’ contracts, the companies’ liquidity position, the companies’ ability to obtain new contracts, the emergence of competitors with greater financial resources and the impact of competitive pricing. In the light of these uncertainties, the forward-looking events referred to in this release might not occur. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Contact:
Puration, Inc.
Brian Shibley,
info@aciconglomerated.com
(800) 861-1350

Source: https://otcprwire.com/pura-concludes-farmersville-meetings-deal-imminent/

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